Cefalu W T
Endocrine, Diabetes, and Metabolism Unit, Department of Medicine, University of Vermont College of Medicine, One South Prospect Street, Burlington, VT 05401, USA.
J Womens Health Gend Based Med. 2001 Apr;10(3):241-55. doi: 10.1089/152460901300139998.
In healthy postmenopausal women, estrogen or hormone replacement therapy (ERT or HRT) can alleviate menopausal symptoms and prevent osteoporosis and may also protect against cardiovascular disease (CVD). In addition to improving lipid metabolism, there are reports that estrogen also improves parameters regulating carbohydrate metabolism, including insulin resistance, in healthy women. Therefore, it is likely that ERT or HRT would also benefit women with type 2 diabetes, not only in relieving menopausal symptoms but also in improving the metabolic abnormalities associated with diabetes and in preventing cardiovascular disease.
在健康的绝经后女性中，雌激素或激素替代疗法（ERT或HRT）可以缓解更年期症状、预防骨质疏松症，还可能预防心血管疾病（CVD）。除了改善脂质代谢外，有报道称雌激素还能改善调节碳水化合物代谢的参数，包括健康女性的胰岛素抵抗。因此，ERT或HRT可能也会使2型糖尿病女性受益，不仅能缓解更年期症状，还能改善与糖尿病相关的代谢异常以及预防心血管疾病。
