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一种用于在行为猴中构建用于可逆失活的微电极的简单方法。

A simple method for constructing microinjectrodes for reversible inactivation in behaving monkeys.

作者信息

Chen L L, Goffart L, Sparks D L

机构信息

Division of Neuroscience, Baylor College of Medicine, Houston, TX 77030, USA.

出版信息

J Neurosci Methods. 2001 May 30;107(1-2):81-5. doi: 10.1016/s0165-0270(01)00354-5.

Abstract

A method for constructing a simple, durable injection-microelectrode (injectrode) is described. The injectrode can record neuronal activity, stimulate neuronal tissues, or inject substances locally through its tip. The injectrode is lightweight and is easy to construct from commercially available parts, and it can be used repeatedly for multiple recordings and injections. Since dura penetration can damage fragile electrode tips, a reliable method to pass the injectrode through an intact dura matter is described.

摘要

描述了一种构建简单、耐用的注射微电极(注入电极)的方法。该注入电极可以记录神经元活动、刺激神经元组织或通过其尖端局部注射物质。该注入电极重量轻,易于用市售部件构建,并且可以重复用于多次记录和注射。由于穿透硬脑膜会损坏脆弱的电极尖端,因此描述了一种使注入电极穿过完整硬脑膜的可靠方法。

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