Rebec G V, Langley P E, Pierce R C, Wang Z, Heidenreich B A
Department of Psychology, Indiana University, Bloomington 47405.
J Neurosci Methods. 1993 Apr;47(1-2):53-9. doi: 10.1016/0165-0270(93)90021-i.
An inexpensive, easily fabricated micromanipulator is described that can be used for single-unit recording or voltammetry in freely moving rats. The basic design is configured around the standard coupling system between a plastic syringe and corresponding needle hub. The device can be used with glass or metal microelectrodes for electrophysiology or carbon-fiber or carbon-disk microelectrodes for voltammetry. With either recording technique, the micromanipulator also can accommodate a 33-ga infusion cannula, which allows drugs to be administered directly to the recording site. The entire assembly is lightweight and can be used with a head-mounted amplifier system for relatively noise-free recording.
本文描述了一种价格低廉、易于制造的微操纵器,可用于自由活动大鼠的单细胞记录或伏安法研究。其基本设计围绕塑料注射器与相应针座之间的标准耦合系统构建。该装置可与玻璃或金属微电极用于电生理学研究,或与碳纤维或碳盘微电极用于伏安法研究。无论采用哪种记录技术,该微操纵器还可容纳一根33号输注套管,从而能够将药物直接注射到记录部位。整个组件重量轻,可与头戴式放大器系统配合使用,以实现相对无噪声的记录。