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Pharmacodynamics, a tool for a better use of antibiotics?

作者信息

Crokaert F

出版信息

Intensive Care Med. 2001 Feb;27(2):340-3. doi: 10.1007/s001340100865.

DOI:10.1007/s001340100865
PMID:11396276
Abstract
摘要

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Pharmacodynamics, a tool for a better use of antibiotics?药效学，一种更好使用抗生素的工具？
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2
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本文引用的文献

1
Pharmacokinetic and pharmacodynamic modelling of antibiotic therapy.抗生素治疗的药代动力学和药效学建模。
Curr Opin Infect Dis. 1998 Dec;11(6):673-80. doi: 10.1097/00001432-199812000-00005.
2
Low cefpirome levels during twice daily dosing in critically ill septic patients: pharmacokinetic modelling calls for more frequent dosing.重症脓毒症患者每日两次给药时头孢匹罗水平较低：药代动力学模型表明需要更频繁给药。
Intensive Care Med. 2001 Feb;27(2):363-70. doi: 10.1007/s001340000741.
3
Determinants of ceftazidime clearance by continuous venovenous hemofiltration and continuous venovenous hemodialysis.
持续静静脉血液滤过和持续静静脉血液透析清除头孢他啶的决定因素。
Antimicrob Agents Chemother. 2000 Jun;44(6):1639-44. doi: 10.1128/AAC.44.6.1639-1644.2000.
4
Pharmacokinetics of cefpirome during the posttraumatic systemic inflammatory response syndrome.头孢匹罗在创伤后全身炎症反应综合征期间的药代动力学
Intensive Care Med. 1999 May;25(5):486-91. doi: 10.1007/s001340050885.
5
Emergence of antibiotic-resistant Pseudomonas aeruginosa: comparison of risks associated with different antipseudomonal agents.耐抗生素铜绿假单胞菌的出现：不同抗假单胞菌药物相关风险的比较。
Antimicrob Agents Chemother. 1999 Jun;43(6):1379-82. doi: 10.1128/AAC.43.6.1379.
6
Evaluation of several dosing regimens of cefepime, with various simulations of renal function, against clinical isolates of Pseudomonas aeruginosa in a pharmacodynamic infection model.在药效学感染模型中，针对铜绿假单胞菌临床分离株，评估头孢吡肟的几种给药方案，并对肾功能进行各种模拟。
Antimicrob Agents Chemother. 1999 Jan;43(1):129-33. doi: 10.1128/AAC.43.1.129.
7
A new approach to in vitro comparisons of antibiotics in dynamic models: equivalent area under the curve/MIC breakpoints and equiefficient doses of trovafloxacin and ciprofloxacin against bacteria of similar susceptibilities.动态模型中抗生素体外比较的新方法：曲线下等效面积/MIC断点以及曲伐沙星和环丙沙星针对相似敏感性细菌的等效剂量
Antimicrob Agents Chemother. 1998 Nov;42(11):2841-7. doi: 10.1128/AAC.42.11.2841.
8
The pharmacodynamics of beta-lactams.β-内酰胺类药物的药效学
Clin Infect Dis. 1998 Jul;27(1):10-22. doi: 10.1086/514622.
9
Comparisons between antimicrobial pharmacodynamic indices and bacterial killing as described by using the Zhi model.使用智模型描述的抗菌药物动力学指标与细菌杀灭之间的比较。
Antimicrob Agents Chemother. 1998 Jul;42(7):1731-7. doi: 10.1128/AAC.42.7.1731.
10
Pharmacodynamic evaluation of factors associated with the development of bacterial resistance in acutely ill patients during therapy.急性病患者治疗期间与细菌耐药性产生相关因素的药效学评价。
Antimicrob Agents Chemother. 1998 Mar;42(3):521-7. doi: 10.1128/AAC.42.3.521.