Schwarz S, Kehrenberg C, Walsh T R
Institut für Tierzucht und Tierverhalten, Bundesforschungsanstalt für Landwirtschaft (FAL), Dörnbergstr. 25-27, 29223, Celle, Germany.
Int J Antimicrob Agents. 2001 Jun;17(6):431-7. doi: 10.1016/s0924-8579(01)00297-7.
Antimicrobial resistance is a growing area of concern in both human and veterinary medicine. This review presents an overview of the use of antimicrobial agents in animals for therapeutic, metaphylactic, prophylactic and growth promotion purposes. In addition, factors favouring resistance development and transfer of resistance genes between different bacteria, as well as transfer of resistant bacteria between different hosts, are described with particular reference to the role of animals as a reservoir of resistance genes or resistant bacterial pathogens which may cause diseases in humans.
抗菌药物耐药性是人类医学和兽医学中一个日益受到关注的领域。本综述概述了抗菌药物在动物治疗、群体预防、预防和促进生长方面的应用。此外,还描述了有利于耐药性发展以及耐药基因在不同细菌之间转移的因素,以及耐药细菌在不同宿主之间转移的因素,特别提及了动物作为耐药基因或耐药细菌病原体储存库的作用,这些病原体可能导致人类疾病。