产β-内酰胺酶细菌及细菌干扰在链球菌性扁桃体炎中的作用
The role of beta-lactamase producing bacteria and bacterial interference in streptococcal tonsillitis.
作者信息
Brook I
机构信息
Department of Pediatrics, Georgetown University School of Medicine, 4431 Albemarle Street, Washington, DC 20016, USA.
出版信息
Int J Antimicrob Agents. 2001 Jun;17(6):439-42. doi: 10.1016/s0924-8579(01)00321-1.
Abstract
The causes of penicillin failure in eradicating group A beta-haemolytic streptococcal pharyngo-tonsillitis are described. The mechanisms accounting for the failure include the presence in the tonsils of beta-lactamase producing bacteria and the absence of bacterial interference. The use of antimicrobials that can overcome and modulate these two phenomena and achieve better cure of the infection is described.
摘要
本文描述了青霉素在根除A组β溶血性链球菌性咽扁桃体炎时失效的原因。导致失效的机制包括扁桃体中存在产β-内酰胺酶的细菌以及缺乏细菌干扰。文中还介绍了使用能够克服和调节这两种现象并更好地治愈感染的抗菌药物的情况。
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