在使用泰利霉素或阿莫西林-克拉维酸对急性上颌窦炎进行抗菌治疗后，鼻咽部干扰细菌的恢复情况。
Recovery of interfering bacteria in the nasopharynx following antimicrobial therapy of acute maxillary sinusitis with telithromycin or amoxicillin-clavulanate.
作者信息
Brook Itzhak, Hausfeld Jeffrey N
机构信息
Georgetown University School of Medicine, Washington, DC 20016, USA.
出版信息
Antimicrob Agents Chemother. 2005 Nov;49(11):4793-4. doi: 10.1128/AAC.49.11.4793-4794.2005.
Abstract
The effect on the nasopharyngeal flora of 7 days of amoxicillin-clavulanate or 5 days of 800 mg once a day was studied in 50 adults with acute sinusitis. The numbers of potential pathogens and interfering alpha-hemolytic streptococci were equally reduced after both therapies. However, the number of interfering Prevotella spp. declined more significantly after amoxicillin-clavulanate treatment.
摘要
在50名患有急性鼻窦炎的成年人中，研究了阿莫西林-克拉维酸盐治疗7天或每天一次服用800毫克、持续5天对鼻咽部菌群的影响。两种治疗后，潜在病原体和干扰性α溶血性链球菌的数量均同等减少。然而，阿莫西林-克拉维酸盐治疗后，干扰性普雷沃菌属的数量下降更为显著。
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