Hamard P, Tazartes M, Ayed T, Quesnot S, Hamard H
Centre Hospitalier National d'Ophtalmologie des Quinze-Vingts, 28, rue de Charenton, 75012 Paris.
J Fr Ophtalmol. 2001 May;24(5):482-90.
Late bleb leaks may follow months to years after filtering surgery especially with the use of antimetabolites. Complications related to beb leaks may lead to a decrease in visual acuity through complicated hypotony or ocular infection. Our retrospective study reports the anatomical and functional results of bleb reconstruction involving the resection of the bleb associated with the covering of the trabeculectomy site with a rotational conjunctival flap.
and methods: Twelve eyes of eleven patients with filtering bleb leaks occurring 3 months to 5 years after successful trabeculectomy (58.3% with adjunct of antimetabolites) underwent bleb surgical reconstruction between november 1995 and June 1999 and were followed until March 2000. Surgical bleb reconstruction was indicated because of persistent or a recurring bleb leak despite conservative medical treatment and blood bleb injections in seven cases. Complications associated with bleb leaks were chronical hypotony (9 cases), athalamy (1 case), hypotony maculopathy (1 case), and endophtalmitis with athalamy (1 case). Three patients had normal IOP but a bleb leak responsible for epiphora. All eyes were treated surgically through bleb excision and conjunctival closure was performed by rotational conjunctival flap.
Mean (+/- SD) preoperative IOP was 5.1+/-3.5mmHg (range: 2 to 14mmHg). Mean (+/- SD) postoperative IOP evaluated before any other operation for uncontrolled IOP was 12.7+/-3.1mmHg (range: 6 to 15mmHg). Mean follow-up was 26.7+/-16.9 months (range: 9 to 64 months). All the complications related to the bleb leak resolved after bleb reconstruction. Surgery definively stopped the leak in 10 cases (83.3%) and allowed IOP control without treatment in 50.0% of the cases. Chronic recurring bleb leaks without hypotony occurred in two eyes and required surgery with conjunctival graft which led to a refractory increase in IOP responsible for loss of vision in one case.
Bleb resection associated with the covering of the trabeculectomy site with a rotational conjunctival flap is a safe and effective procedure for the treatment of a late bleb leak and its complications. In most of the cases (83.3%), long-term IOP control can be expected without, medical treatment in 50% of the cases. Patients must be aware of the possibility of a recurring Seidel; however, the incidence of this complication remains low.
滤过性手术后数月至数年可能会出现迟发性滤过泡渗漏,尤其是在使用抗代谢药物的情况下。与滤过泡渗漏相关的并发症可能会通过复杂的低眼压或眼部感染导致视力下降。我们的回顾性研究报告了滤过泡重建的解剖学和功能结果,该重建包括切除滤过泡,并使用旋转结膜瓣覆盖小梁切除术部位。
11例患者的12只眼在小梁切除术成功后3个月至5年出现滤过泡渗漏(58.3%使用了抗代谢药物辅助治疗),于1995年11月至1999年6月接受了滤过泡手术重建,并随访至2000年3月。7例患者因尽管进行了保守药物治疗和血液滤过泡注射,但滤过泡渗漏仍持续或复发而进行手术滤过泡重建。与滤过泡渗漏相关的并发症包括慢性低眼压(9例)、无晶状体眼(1例)、低眼压性黄斑病变(1例)和伴有无晶状体眼的眼内炎(1例)。3例患者眼压正常,但滤过泡渗漏导致流泪。所有眼睛均通过切除滤过泡进行手术治疗,并使用旋转结膜瓣进行结膜闭合。
术前平均(±标准差)眼压为5.1±3.5mmHg(范围:2至14mmHg)。在因眼压控制不佳而进行任何其他手术之前评估的术后平均(±标准差)眼压为12.7±3.1mmHg(范围:6至15mmHg)。平均随访时间为26.7±16.9个月(范围:9至64个月)。滤过泡重建后,所有与滤过泡渗漏相关的并发症均得到解决。手术在10例(83.3%)患者中彻底止住了渗漏,50.0%的患者无需治疗即可控制眼压。2只眼出现无低眼压的慢性复发性滤过泡渗漏,需要进行结膜移植手术,其中1例导致眼压难治性升高,造成视力丧失。
切除滤过泡并使用旋转结膜瓣覆盖小梁切除术部位是治疗迟发性滤过泡渗漏及其并发症的一种安全有效的方法。在大多数病例(83.3%)中,预计50%的患者无需药物治疗即可长期控制眼压。患者必须意识到可能会出现复发性Seidel征;然而,这种并发症的发生率仍然很低。