Sundberg J P, King L E, Bascom C
The Jackson Laboratory, 600 Main Street, Bar Harbor, ME 04609-1500, USA.
Eur J Dermatol. 2001 Jul-Aug;11(4):321-5.
The stump-tailed macaque (Macaca arctoides) appears to be a suitable biological model for human androgenetic alopecia. The expense, danger, and low availability compromise its value but macaques currently remain the model of choice. Rodent models, both testosterone induced alopecia and various xenograft approaches, show promise for elucidating fundamental information on normal and abnormal hair growth as well as serving as models to develop new therapies to treat hair loss.
短尾猕猴(食蟹猴)似乎是人类雄激素性脱发的合适生物学模型。其成本、危险性和低可用性降低了它的价值,但猕猴目前仍是首选模型。啮齿动物模型,无论是睾酮诱导的脱发模型还是各种异种移植方法,在阐明正常和异常毛发生长的基本信息方面都很有前景,同时也可作为开发治疗脱发新疗法的模型。