Ranzini A C, Ananth C V, Smulian J C, Kung M, Limbachia A, Vintzileos A M
Division of Maternal-Fetal Medicine, University of Medicine and Dentistry of New Jersey-Robert Wood Johnson Medical School/Saint Peter's University Hospital, New Brunswick 08903-0591, USA.
J Ultrasound Med. 2001 Jun;20(6):613-7. doi: 10.7863/jum.2001.20.6.613.
To describe gestational age-dependent and -independent nomograms for fetal thyroid size.
Two hundred fetuses were evaluated between 16 and 37 weeks' gestation in this cross-sectional study.
Nomograms of fetal thyroid size were created by using the 5th, 10th, 50th, 90th, and 95th percentiles based on biparietal diameter and gestational age. A second-order polynomial fit for biparietal diameter and a linear fit for gestational age best described thyroid circumference measurements. Variations in thyroid circumference measurements increased with both larger biparietal diameter and advancing gestational age. There was no intraobserver or interobserver variability in thyroid circumference measurements (P > .20).
Both biparietal diameter and gestational age serve as good predictors of fetal thyroid circumference. When the biparietal diameter is difficult to measure, gestational age can be used to assess thyroid size.
描述胎儿甲状腺大小与孕周相关和不相关的列线图。
在这项横断面研究中，对200例孕16至37周的胎儿进行了评估。
基于双顶径和孕周，使用第5、10、50、90和95百分位数创建了胎儿甲状腺大小的列线图。对双顶径采用二阶多项式拟合，对孕周采用线性拟合能最好地描述甲状腺周长测量值。甲状腺周长测量值的变异随双顶径增大和孕周增加而增加。甲状腺周长测量值不存在观察者内或观察者间差异（P>.20）。
双顶径和孕周都是胎儿甲状腺周长的良好预测指标。当双顶径难以测量时，孕周可用于评估甲状腺大小。
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