Stimulation of bone resorption in organ culture by salt-free extracts of Solanum glaucophyllum.

Addition of a desalted aqueous extract made from dried leaves of Solanum glaucophyllum produced a marked stimulation of bone resorption in a culture system in vitro. This result indicates that, like the biologically active forms of vitamin D, the active material in the plant not only stimulates intestinal calcium absorption but increases bone mobilization as well.