L5/S1神经根病中肌无力的电生理相关性

Electrophysiologic correlates of weakness in L5/S1 radiculopathy.

作者信息

Scelsa S N, Berger A R, Herskovitz S

机构信息

Department of Neurology, Albert Einstein College of Medicine, Bronx, New York, Beth Israel Medical Center.

出版信息

Electromyogr Clin Neurophysiol. 2001 Apr-May;41(3):145-51.

PMID:11402506

Abstract

INTRODUCTION

Management of patients with radiculopathy involves estimating the degree of physiologic and anatomic injury, and weighing that to predict the likely clinical course.

OBJECTIVE

To determine whether low distal peroneal and tibial CMAP amplitudes correlate with weakness and fibrillations of functionally relevant muscles in L5/S1 radiculopathy (LSR).

METHODS

We reviewed clinical and electrophysiologic data in 66 consecutive patients with LSR.

RESULTS

A significantly greater number of patients with low peroneal CMAP amplitudes had weakness of L5 (p = 0.025) and S1 innervated leg muscles (p < 0.001). Low tibial CMAP amplitudes were also associated with weakness of S1 innervated muscles (p < 0.038). The association of low peroneal CMAP amplitudes with weakness persisted when weakness of at least 3 muscles was considered in the analysis for L5 (p < 0.0001) and S1 (p = 0.014) innervated muscles.

CONCLUSIONS

Low peroneal and tibial CMAP amplitudes may serve as surrogate measures for segmental weakness of functionally relevant muscles in LSR.

摘要

引言

神经根病患者的管理包括评估生理和解剖损伤的程度，并权衡这些因素以预测可能的临床病程。

目的

确定低位腓总神经和胫神经复合肌肉动作电位（CMAP）波幅是否与L5/S1神经根病（LSR）中功能相关肌肉的无力和纤颤电位相关。

方法

我们回顾了66例连续性LSR患者的临床和电生理数据。

结果

腓总神经CMAP波幅低的患者中，L5支配的腿部肌肉无力（p = 0.025）和S1支配的腿部肌肉无力（p < 0.001）的患者数量显著更多。胫神经CMAP波幅低也与S1支配的肌肉无力相关（p < 0.038）。在分析L5支配的肌肉（p < 0.0001）和S1支配的肌肉（p = 0.014）时，当考虑至少3块肌肉无力时，腓总神经CMAP波幅低与无力之间的关联仍然存在。