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[尿道尖锐湿疣。一项治疗挑战]

[Urethral condylomas. A therapeutic challenge].

作者信息

Schneede P, Münch P, Ziller F, Hofstetter A

机构信息

Klinik für Urologie, Klinikum der Universität München, Marchioninistrasse 15, 81377 München, Grosshadern.

出版信息

Hautarzt. 2001 May;52(5):411-7. doi: 10.1007/s001050051334.

DOI:10.1007/s001050051334
PMID:11405159
Abstract

BACKGROUND AND OBJECTIVE

Very diverse treatment recommendations exist in the literature on HPV lesions of the urethra. There are no treatment guidelines from the specialist societies. Both these factors have led to a very wide spectrum of heterogeneous treatment strategies in hospitals and medical practices of various specialties. Primary and secondary treatment of urethral condylomata by practitioners as well as a specialized HPV center was evaluated.

PATIENTS/METHODS: One hundred and five patients with condylomata of the urethra were studied. Most had been previously treated, often several times, by a variety of specialists. We treated all regardless of prior treatment status with laser therapy.

RESULTS

A high percentage of patients treated with different methods in medical practices but also at our high-technology center sometimes showed serious treatment complications and numerous recurrences. Most established methods of treatment for condylomata on the external genitalia are not necessarily applicable to the urethra.

CONCLUSIONS

About 20% of urethral condylomata can only be reached by endoscopy. Co-existing urethral malformations as well as complications of therapy are reasons for early cooperation with the urologist or HPV center.

摘要

背景与目的

关于尿道人乳头瘤病毒(HPV)病变的文献中存在非常多样的治疗建议。专业学会没有治疗指南。这两个因素导致不同专科的医院和医疗实践中存在非常广泛的异质性治疗策略。评估了从业者以及一家专门的HPV中心对尿道尖锐湿疣的一级和二级治疗。

患者/方法:研究了105例尿道尖锐湿疣患者。大多数患者此前曾由各种专科医生进行过治疗,且常常是多次治疗。我们对所有患者进行了激光治疗,无论其先前的治疗情况如何。

结果

在医疗实践中以及在我们的高科技中心,采用不同方法治疗的患者中,有很大比例有时会出现严重的治疗并发症和大量复发。大多数已确立的治疗外生殖器尖锐湿疣的方法不一定适用于尿道。

结论

约20%的尿道尖锐湿疣只能通过内镜检查触及。并存的尿道畸形以及治疗并发症是早期与泌尿科医生或HPV中心合作的原因。

相似文献

1
[Urethral condylomas. A therapeutic challenge].[尿道尖锐湿疣。一项治疗挑战]
Hautarzt. 2001 May;52(5):411-7. doi: 10.1007/s001050051334.
2
Extensive condylomas acuminata of the entire male urethra and the bladder.累及整个男性尿道及膀胱的广泛尖锐湿疣。
J Urol. 1974 Aug;112(2):201-3. doi: 10.1016/s0022-5347(17)59684-6.
3
Laser treatment of recurrent urethral condylomata acuminata in men.男性复发性尿道尖锐湿疣的激光治疗
Scand J Urol Nephrol. 1990;24(3):163-6. doi: 10.3109/00365599009180851.
4
Recurrence of condylomata acuminata of the urethra after conventional and fluorescence-controlled Nd:YAG laser treatment.常规及荧光控制钕钇铝石榴石激光治疗后尿道尖锐湿疣的复发情况
Urology. 2003 May;61(5):1011-5. doi: 10.1016/s0090-4295(02)02527-x.
5
Treatment of condylomata acuminata with the carbon dioxide laser.二氧化碳激光治疗尖锐湿疣
Br J Obstet Gynaecol. 1984 Feb;91(2):193-6. doi: 10.1111/j.1471-0528.1984.tb05906.x.
6
Extensive condylomata acuminata of male urethra: management by ventral urethrotomy.
Br J Urol. 1993 Feb;71(2):204-7. doi: 10.1111/j.1464-410x.1993.tb15919.x.
7
Continuous wave carbon dioxide laser treatment of giant condylomata acuminata of the distal urethra and perineum: technique.连续波二氧化碳激光治疗远端尿道及会阴部巨大尖锐湿疣:技术
J Urol. 1981 Dec;126(6):827-9. doi: 10.1016/s0022-5347(17)54769-2.
8
[Hormone disorders and HPV infection. Risk factors for tumors of the urethra?].[激素紊乱与HPV感染。尿道肿瘤的危险因素?]
MMW Fortschr Med. 2003 Jan 30;145(5):36-8.
9
[Condylomata acuminata--with special reference to intraurethral condylomata acuminata].[尖锐湿疣——特别提及尿道内尖锐湿疣]
Ugeskr Laeger. 1982 Nov 22;144(47):3493-6.
10
Using the laser to treat vulvar condylomata acuminata and intraepidermal neoplasia.使用激光治疗外阴尖锐湿疣和表皮内瘤变。
Can Med Assoc J. 1983 Jan 15;128(2):135-7.

引用本文的文献

1
Electrocoagulation Therapy for Urethral Condyloma Acuminata in a Male Patient: Case Report.男性患者尿道尖锐湿疣的电凝治疗:病例报告
Clin Med Insights Case Rep. 2024 Oct 18;17:11795476241292903. doi: 10.1177/11795476241292903. eCollection 2024.
2
[Human papillomavirus disease burden in men : HPV prevention is a man's business].男性人乳头瘤病毒疾病负担:预防人乳头瘤病毒关乎男性自身
Urologe A. 2018 Dec;57(12):1452-1456. doi: 10.1007/s00120-018-0770-8.
3
[Anogenital warts and HPV-associated precancers : Looking into the recently passed German S2k guideline].
[肛门生殖器疣和人乳头瘤病毒相关癌前病变:解读最新通过的德国S2k指南]
Urologe A. 2018 Apr;57(4):453-457. doi: 10.1007/s00120-018-0580-z.
4
[Proven and new methods in the treatment of genital warts].[尖锐湿疣治疗的成熟方法与新方法]
Urologe A. 2013 Oct;52(10):1416-21. doi: 10.1007/s00120-013-3174-9.
5
[HPV in urology. Basic principles and controversies].[泌尿外科中的人乳头瘤病毒。基本原则与争议]
Urologe A. 2013 Sep;52(9):1329-36: quiz 1337-8. doi: 10.1007/s00120-013-3257-7.
6
[Condylomata acuminata: an indication for prophylactic HPV vaccination?].[尖锐湿疣:预防性人乳头瘤病毒疫苗接种的一个指征?]
Urologe A. 2006 Dec;45(12):1514-20. doi: 10.1007/s00120-006-1232-2.