Tan J H, Ho K H
Department of Medicine, National University Hospital, Singapore.
Singapore Med J. 2001 Mar;42(3):124-5.
Our two patients presented with Wernicke's Encephalopathy (WE) resulting from prolonged hyperemesis gravidarum. This is an unusual cause of WE, a potentially fatal medical emergency due to thiamine deficiency. We discuss the clinical settings, presentation, diagnosis, neurophysiological and radiological findings, treatment and outcome of WE in these two cases and the neuropathologic correlation of this condition. We stress upon the importance of early diagnosis and prompt treatment of WE.
我们的两名患者因妊娠剧吐时间延长而出现韦尼克脑病(WE)。这是韦尼克脑病的一种不寻常病因,是一种因硫胺素缺乏而导致的潜在致命性医疗急症。我们讨论了这两例韦尼克脑病的临床背景、表现、诊断、神经生理学和影像学检查结果、治疗及预后,以及该病的神经病理学关联。我们强调早期诊断和及时治疗韦尼克脑病的重要性。