Kobayashi Y
First Department of Internal Medicine, School of Medicine, Ehime University, Ehime, Japan.
J Infect Chemother. 2001 Mar;7(1):10-5. doi: 10.1007/s101560170028.
On January 20, 1915, Inada and Ido announced the discovery of the causative agent of Weil's disease. Subsequently, on February 13, 1915, they published the first paper on the discovery of the causative organism (a new species of Spirochaeta) of Weil's disease. Besides discovering the causative organism of the disease, Inada and colleagues clarified the pure culture in medium, and determined the source and route of the infection, its pathology and morbid anatomy; the distribution of the organism in various organs and tissues; the excretion of the spirochete, and its division, filterability, and morphological characteristics; and the clinical picture, laboratory findings, diagnosis, prophylaxis, and treatment of the disease. These studies were conducted by Inada, Ido, Kaneko, Hoki, and Ito, in the years 1914 to 1915. In the early investigation of leptospirosis, Inada and colleagues played a prominent part. We would like to remember these remarkably complete and definitive original achievements on leptospirosis made by Inada and colleagues.
1915年1月20日，稻田和伊东宣布发现了韦尔氏病的病原体。随后，1915年2月13日，他们发表了第一篇关于发现韦尔氏病病原体（一种新的螺旋体属物种）的论文。除了发现该疾病的病原体外，稻田及其同事还阐明了该病原体在培养基中的纯培养，确定了感染源和感染途径、其病理学和病理解剖学；该病原体在各种器官和组织中的分布；螺旋体的排泄情况，以及其分裂、滤过性和形态特征；以及该疾病的临床表现、实验室检查结果、诊断、预防和治疗。这些研究是由稻田、伊东、金子、保木和伊藤在1914年至1915年期间进行的。在钩端螺旋体病的早期研究中，稻田及其同事发挥了突出作用。我们谨铭记稻田及其同事在钩端螺旋体病方面取得的这些极其完整和明确的原始成就。
