Chabrol H, Chouicha K, Montovany A, Callahan S
Centre d'Etude et de Recherche en Psychopathologie, Université de Toulouse-Le Mirail, 5, allée Antonío Machado, 31058 Toulouse.
Encephale. 2001 Mar-Apr;27(2):120-7.
1,363 high school students were solicited to complete a personality disorder questionnaire and were encouraged to continue in the study by signing up for interviews with Master's level psychology students. 107 students (7.8%, 34 males, 73 females, mean age = 16.7 +/- 1.8) manifested themselves for the interview and were assessed by using structured diagnostic interviews for borderline personality disorder and major depressive disorder (DIB-R, Revised Diagnostic Interview for Borderlines; MINI, Mini International Neuropsychiatric Interview). The interviews were audiotaped. Interrater reliability was determined by independent ratings of 12 borderline subjects and 12 non-borderline subjects (kappa: 0.795). The distribution of the 107 subjects based on the number of DSM IV borderline personality disorder criteria indicated a gradual dispersion suggesting a continuum from normality to borderline personality disorder: 8% of the subjects met none of the criteria; 16% met one criterion; 17% met two; 12.5%, three; 13.7%, four; 8.4%, five; 5.6%, six; 9.3%, seven; 4.6%, eight; 4.6%, nine. Thirty-five of these 107 subjects (32.7%, 6 males, 29 females, mean age = 16.7 +/- 1.7) received a diagnosis of borderline personality disorder according to DSM IV criteria. The most frequent symptoms were paranoid ideation or dissociative symptoms (97.1%), affective instability (88.6%), inappropriate, intense anger (85.6%), suicidal gestures or automutilation (82.9%), followed by frantic efforts to avoid abandonment (77%), impulsivity (65.7%), unstable and intense relationships (62.9%), identity disturbance (60%), and emptiness (57.1%). The comparison between borderline and non-borderline subjects showed that all borderline personality disorder criteria discriminated significantly between the two groups. The high incidence of paranoid ideation (97.1%) and dissociative experiences (65.7%) in the borderline group suggests the pertinence of criterion 9 in the diagnosis of borderline personality disorder in adolescents. Two criteria of schizotypal personality disorder were also frequent in this group: 68.6% of the borderline group reported odd beliefs or magical thinking, in particular beliefs in clairvoyance or telepathy and 88.6% reported unusual perceptual experiences, in particular sensing the presence of a force or person and bodily illusions. Moreover, 31.4% of the borderline group reported transient "quasi" psychotic experiences, mainly "quasi" visual hallucinations. Auditory hallucinations or delusional ideas were not observed. This symptomatology suggests a "quasi" psychotic dimension of adolescent borderline personality disorder. Affective instability was the next most frequent symptom which was usually marked by a cyclothymic appearance. Comorbidity with major depressive disorder was high: 85.7% of the borderline subjects had a concurrent diagnosis of major depression versus 45.8% of the non-borderline subjects. Thus, major depression is more frequent than most of the borderline personality disorder criteria, with the exception of the already noted paranoid ideation and affective instability. Hypomanic symptoms were frequent in the borderline group (65.7%) as well as in the non-borderline group (38.8%). This symptomatology suggests that adolescent borderline personality disorder is linked to an attenuated bipolar spectrum characterised by major depressive episodes and soft signs of bipolarity. However, hypomanic symptoms, which were quite frequent in non-borderline subjects, might also be due to a mechanism of defence, i.e. the denial of depression. Comorbidity with anxiety disorders appeared also to be high: anxiety symptoms were found in 91.4% of the borderline subjects who reported symptoms of generalised anxiety disorder, panic disorder, and somatoform disorders. The overall clinical appearance of these borderline adolescents not referred for treatment seemed to be quite similar to that of borderline adolescents in clinical samples. This study shows that adolescent borderline personality disorder in non-clinical population is a serious disorder characterised by the importance of mental suffering and behavioural disturbances the disorganising power of which may fix the developmental process in a pathological pathway. Adolescent borderline personality disorder appears in this study to be strongly associated with major depressive disorder and at-risk behaviours linked to impulsivity, affective instability, and suicidal ideation. However, this study found an absence of precise cut-off between borderline and non-borderline subjects. Two factors might have contributed to the appearance of a continuum. First, some degree of impulsivity and instability in affectivity, self-images and interpersonal relationships is part of normal adolescence. (ABSTRACT TRUNCATED)
1363名高中生被邀请填写一份人格障碍问卷,并被鼓励通过报名参加与心理学硕士研究生的访谈来继续参与研究。107名学生(7.8%,男性34名,女性73名,平均年龄 = 16.7 ± 1.8岁)报名参加访谈,并通过使用针对边缘型人格障碍和重度抑郁症的结构化诊断访谈(DIB-R,修订版边缘型人格障碍诊断访谈;MINI,迷你国际神经精神病学访谈)进行评估。访谈进行了录音。通过对12名边缘型受试者和12名非边缘型受试者的独立评分确定了评分者间信度(kappa值:0.795)。根据DSM-IV边缘型人格障碍标准的数量对107名受试者进行的分布显示出一种逐渐分散的趋势,表明从正常到边缘型人格障碍存在一个连续体:8%的受试者未符合任何标准;16%符合一项标准;17%符合两项;12.5%符合三项;13.7%符合四项;8.4%符合五项;5.6%符合六项;9.3%符合七项;4.6%符合八项;4.6%符合九项。这107名受试者中有35名(32.7%,男性6名,女性29名,平均年龄 = 16.7 ± 1.7岁)根据DSM-IV标准被诊断为边缘型人格障碍。最常见的症状是偏执观念或分离症状(97.1%)、情感不稳定(88.6%)、不适当的强烈愤怒(85.6%)、自杀姿态或自残行为(82.9%),其次是疯狂努力避免被抛弃(77%)、冲动性(65.7%)、不稳定且强烈的人际关系(62.9%)、身份认同紊乱(60%)和空虚感(57.1%)。边缘型与非边缘型受试者之间的比较表明,所有边缘型人格障碍标准在两组之间都有显著差异。边缘型组中偏执观念(97.1%)和分离体验(65.7%)的高发生率表明标准9在青少年边缘型人格障碍诊断中的相关性。分裂样人格障碍的两项标准在该组中也很常见:68.6%的边缘型组报告有怪异信念或神奇思维,特别是对透视或心灵感应的信念,88.6%报告有异常的感知体验,特别是感觉到一种力量或人的存在以及身体幻觉。此外,31.4%的边缘型组报告有短暂的“准”精神病性体验,主要是“准”视幻觉。未观察到听幻觉或妄想观念。这种症状学表明青少年边缘型人格障碍存在“准”精神病性维度。情感不稳定是接下来最常见的症状,通常表现为环性心境障碍的外观。与重度抑郁症的共病率很高:85.7%的边缘型受试者同时被诊断为重度抑郁症,而非边缘型受试者为45.8%。因此,除了已经提到的偏执观念和情感不稳定外,重度抑郁症比大多数边缘型人格障碍标准更常见。轻躁狂症状在边缘型组(65.7%)和非边缘型组(38.8%)中都很常见。这种症状学表明青少年边缘型人格障碍与以重度抑郁发作和双相情感障碍的软性症状为特征的轻度双相谱系有关。然而,轻躁狂症状在非边缘型受试者中也很常见,这也可能是由于一种防御机制,即对抑郁的否认。与焦虑症的共病率似乎也很高:在报告有广泛性焦虑症、惊恐障碍和躯体形式障碍症状的边缘型受试者中,91.4%发现有焦虑症状。这些未被转诊治疗的边缘型青少年的总体临床表现似乎与临床样本中的边缘型青少年非常相似。这项研究表明,非临床人群中的青少年边缘型人格障碍是一种严重的障碍,其特征在于精神痛苦和行为障碍的重要性,其破坏组织的力量可能会使发育过程陷入病理途径。在这项研究中,青少年边缘型人格障碍似乎与重度抑郁症以及与冲动性、情感不稳定和自杀观念相关的危险行为密切相关。然而,这项研究发现边缘型与非边缘型受试者之间没有精确的界限。两个因素可能导致了连续体的出现。首先,在情感、自我形象和人际关系方面一定程度的冲动性和不稳定性是正常青春期的一部分。