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在一项针对髋部骨折女性的营养干预研究中,使用生化和人体测量学变量评估营养状况。

Assessment of nutritional status using biochemical and anthropometric variables in a nutritional intervention study of women with hip fracture.

作者信息

Bachrach-Lindström M, Unosson M, Ek A C, Arnqvist H J

机构信息

Department of Medicine and Care, Division of Nursing Studies, University of Linköping, Linköping, Sweden.

出版信息

Clin Nutr. 2001 Jun;20(3):217-23. doi: 10.1054/clnu.2000.0383.

Abstract

BACKGROUND & AIMS: The aim of this study of women with hip fracture was to describe nutritional status with biochemical markers and anthropometric variables, and to evaluate the effect of nutritional intervention with the intention of increasing protein and energy intake.

METHODS

The first consecutive 44 women were included, and used as controls. The next 44 were matched for age, fracture and mental state. Anthropometric variables, IGF-I, hormones and serum albumin were collected 4--6 days (baseline), 1 and 3 months after surgery. Twenty-four women filled out a 7-day food record.

RESULTS

At baseline, one fourth had BMI <20 kg/m(2)and subnormal triceps skinfold thickness. Baseline serum albumin, IGF-I and growth hormone levels were low, probably as an acute response to trauma. Women with BMI <20 kg/m(2)had lower IGF-I levels compared to those with higher BMI. At 3 months, one-third of both groups were protein and energy malnourished. The intervention group obtained higher daily energy percentage from fat but none of the groups reached their calculated energy need.

CONCLUSIONS

Using biochemical markers in the acute postoperative situation to assess nutritional status is not recommended. The intervention had no impact on anthropometric or biochemical variables.

摘要

背景与目的

本研究针对髋部骨折女性,旨在通过生化指标和人体测量学变量描述其营养状况,并评估旨在增加蛋白质和能量摄入的营养干预效果。

方法

纳入首批连续的44名女性作为对照组。接下来的44名女性在年龄、骨折情况和精神状态方面进行了匹配。在术后4 - 6天(基线)、术后1个月和3个月收集人体测量学变量、胰岛素样生长因子-I(IGF-I)、激素和血清白蛋白。24名女性填写了7天的饮食记录。

结果

在基线时,四分之一的女性体重指数(BMI)<20 kg/m² 且肱三头肌皮褶厚度低于正常。基线时血清白蛋白、IGF-I和生长激素水平较低,可能是对创伤的急性反应。BMI<20 kg/m² 的女性与BMI较高的女性相比,IGF-I水平较低。在3个月时,两组中三分之一的女性存在蛋白质和能量营养不良。干预组从脂肪中获取的每日能量百分比更高,但两组均未达到其计算出的能量需求。

结论

不建议在术后急性期使用生化指标评估营养状况。该干预对人体测量学或生化变量没有影响。

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