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股腘动脉搭桥术的长期预后:对349例连续血管重建术的分析

Long-term prognosis of femoropopliteal bypass: an analysis of 349 consecutive revascularizations.

作者信息

Lau H, Cheng S W

机构信息

Department of Surgery, University of Hong Kong Medical Centre, Queen Mary Hospital, Hong Kong.

出版信息

ANZ J Surg. 2001 Jun;71(6):335-40.

Abstract

BACKGROUND

Femoropopliteal bypass is the commonest procedure for lower limb revascularization. The aim of the present study was to determine the long-term outcomes of femoropopliteal bypass and evaluate the prognostic significance of various clinical factors on the long-term results.

METHODS

From 1976 to 1998, 349 consecutive primary femoropopliteal bypass operations were performed on 314 patients at the University of Hong Kong Medical Centre. Indications for operation included claudication (n = 85) and limb-threatening ischaemia (n = 264). Univariate and multivariate analyses of 14 clinical variables were undertaken to identify significant prognostic factors affecting the graft patency, limb salvage and patient survival rates.

RESULTS

The overall primary patency rates of femoropopliteal bypass were 88%, 79% and 76% at 1, 3 and 5 years, respectively. Type of graft material and age of patient were independent prognostic factors of graft patency. The cumulative limb salvage rates were 90%, 86% and 86% at 1, 3 and 5 years, respectively. No clinical factor was found to be predictive of ultimate limb loss. The overall survival rates were 89%, 85% and 78% at 1, 3 and 5 years, respectively. Coronary artery disease was the main cause of late death. Gender and indication for operation were the significant predictive factors of long-term survival.

CONCLUSIONS

Femoropopliteal bypass using reversed long saphenous vein provided the most durable long-term patency. Autologous saphenous vein should be the choice of vascular conduit if available. Male gender and limb-threatening ischaemia were associated with a poor survival.

摘要

背景

股腘动脉搭桥术是下肢血管重建最常见的手术。本研究的目的是确定股腘动脉搭桥术的长期疗效,并评估各种临床因素对长期结果的预后意义。

方法

1976年至1998年,香港大学医学中心对314例患者进行了349例连续的原发性股腘动脉搭桥手术。手术指征包括间歇性跛行(n = 85)和肢体威胁性缺血(n = 264)。对14个临床变量进行单因素和多因素分析,以确定影响移植血管通畅率、肢体挽救率和患者生存率的显著预后因素。

结果

股腘动脉搭桥术的总体原发性通畅率在1年、3年和5年时分别为88%、79%和76%。移植材料类型和患者年龄是移植血管通畅的独立预后因素。累积肢体挽救率在1年、3年和5年时分别为90%、86%和86%。未发现临床因素可预测最终肢体丢失。总体生存率在1年、3年和5年时分别为89%、85%和78%。冠状动脉疾病是晚期死亡的主要原因。性别和手术指征是长期生存的显著预测因素。

结论

使用大隐静脉逆行的股腘动脉搭桥术提供了最持久的长期通畅率。如果可能,自体大隐静脉应作为血管导管的选择。男性和肢体威胁性缺血与生存率低有关。

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