Laprell H, Petersen W
Lubinus Klinik, Hospital for Orthopaedic Surgery, Kiel, Germany.
Arch Orthop Trauma Surg. 2001 May;121(5):248-53. doi: 10.1007/s004020000217.
Thirty-five patients with severe osteochondral defects were treated by autologous osteochondral transplantation between 1986 and 1992. The majority of patients (27) suffered from osteochondrosis dissecans, while 8 patients presented with posttraumatic osteochondral defects. The grafts were harvested with a diamond bone cutter from the posterior part of the medial or lateral femoral condyle. In 29 patients the lesion was located at the lateral part of the medial femoral condyle, in 3 it was at the lateral femoral condyle, and in 3 at the patella. Twenty-nine patients could be examined at the follow-up between 6 and 12 years later (mean follow up 8.1 years). Using the standard cartilage evaluation form, the transplanted knees of 12 patients were graded as normal (grade I), 14 knees were nearly normal (grade II), while 3 patients presented with an abnormal result (grade III). All 3 of them had a varus malalignment and refused a high tibial correction osteotomy against our advice. No patient was assessed as severely abnormal (grade IV). The majority of patients improved their activity level and the functional status of the joint. Twelve patients developed new radiological signs of osteoarthrosis with a decrease in the radiological score of Kellgren and Lawrence by about one stage. We conclude that autologous osteochondral transplantation with the diamond bone-cutting system is an effective method in the treatment of severe osteochondral defects.
1986年至1992年间,35例严重骨软骨缺损患者接受了自体骨软骨移植治疗。大多数患者(27例)患有剥脱性骨软骨炎,8例患者存在创伤后骨软骨缺损。使用金刚石骨刀从股骨内侧髁或外侧髁后部获取移植物。29例患者的病变位于股骨内侧髁外侧部分,3例位于股骨外侧髁,3例位于髌骨。29例患者在6至12年后的随访中接受了检查(平均随访8.1年)。使用标准软骨评估表,12例患者的移植膝关节评分为正常(I级),14例膝关节接近正常(II级),3例患者结果异常(III级)。他们三人都有内翻畸形,不顾我们的建议拒绝进行高位胫骨矫正截骨术。没有患者被评估为严重异常(IV级)。大多数患者的活动水平和关节功能状态有所改善。12例患者出现了骨关节炎的新影像学征象,Kellgren和Lawrence影像学评分下降了约一个等级。我们得出结论,使用金刚石骨切割系统进行自体骨软骨移植是治疗严重骨软骨缺损的有效方法。