Svartman M, Potter E V, Poon-King T, Earle D P
J Clin Invest. 1975 Jul;56(1):111-7. doi: 10.1172/JCI108059.
Three components of complement and six other serum proteins were assayed in synovial fluid and serum samples from 25 patients with acute rheumatic fever in Trinidad. The resulting data indicate a relative decrease in both early and late components of complement within the synovial fluids which suggests local activation by immune complexes. Such activation of complement within the joint spaces may play a primary role in development of the inflammatory arthritis of acute rheumatic fever.
对特立尼达25例急性风湿热患者的滑液和血清样本中的补体的三个成分以及其他六种血清蛋白进行了检测。所得数据表明，滑液中补体的早期和晚期成分均相对减少，这表明免疫复合物可引起局部激活。关节腔内补体的这种激活可能在急性风湿热炎症性关节炎的发展中起主要作用。
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