Chung C P, Hsu S Y, Wu W C
Department of Ophthalmology, Kaohsiung Medical University, No. 100, Shih-Chuan 1st Rd., Kaohsiung, Taiwan.
Kaohsiung J Med Sci. 2001 Feb;17(2):84-9.
To investigate the duration and pattern of cataract formation after pars plana vitrectomy, thirty-three eyes from 33 patients with complete data from March 1995 to January 2000 were collected in this study. The time and pattern of cataract formation was analyzed according to Lens Opacities Classification System III (LOCS III). The correlation between the mean cataract progression and follow-up time was determined by simple regression and correlation analysis. Diabetes mellitus and hypertension were the main causes of patients with vitreoretinopathy who underwent pars plana vitrectomy procedure. Twenty-one patients (63.6%) had diabetes mellitus and 11 patients (33.3%) had hypertension. Four eyes (13.8%) received intravitreal gas injection after pars plana vitrectomy. The correlation between cataract progression and follow-up time was clinically significant (p < 0.05). Thirty-one patients (94%) were nuclear cataract, the mean time of cataract formation being 9.1 months; 15 patients (46.9%) were cortical cataract, the mean time of formation being 8 months; and 24 patients (72.7%) were posterior subcapsular cataract, the mean time of formation being 13.3 months. Cataract formation after pars plana vitrectomy is not infrequent. Nuclear cataract is the most common type in this study. Vitreous microenvironmental changes, post-vitrectomy uveitis, intravitreal gas, and patient age may be the key points of cataract formation after surgery. The mechanism of longer-term effect of pars plana vitrectomy on lens status is still unknown and merits further study.
为了研究玻璃体切割术后白内障形成的持续时间和模式，本研究收集了1995年3月至2000年1月期间33例有完整数据患者的33只眼睛。根据晶状体混浊分级系统III（LOCS III）分析白内障形成的时间和模式。通过简单回归和相关分析确定平均白内障进展与随访时间之间的相关性。糖尿病和高血压是接受玻璃体切割手术的玻璃体视网膜病变患者的主要病因。21例患者（63.6%）患有糖尿病，11例患者（33.3%）患有高血压。4只眼睛（13.8%）在玻璃体切割术后接受了玻璃体腔内气体注射。白内障进展与随访时间之间的相关性具有临床意义（p<0.05）。31例患者（94%）为核性白内障，白内障形成的平均时间为9.1个月；15例患者（46.9%）为皮质性白内障，形成的平均时间为8个月；24例患者（72.7%）为后囊下白内障，形成的平均时间为13.3个月。玻璃体切割术后白内障形成并不罕见。核性白内障是本研究中最常见的类型。玻璃体微环境变化、玻璃体切割术后葡萄膜炎、玻璃体腔内气体和患者年龄可能是术后白内障形成的关键点。玻璃体切割术对晶状体状态的长期影响机制尚不清楚，值得进一步研究。
