Foster R E, Lowder C Y, Meisler D M, Zakov Z N, Meyers S M, Ambler J S
Department of Ophthalmology, Cleveland Clinic Foundation, Ohio 44195-5024.
Ophthalmic Surg. 1993 Jul;24(7):446-52.
The surgical management of coexisting cataract and vitreoretinal disease has been controversial, particularly for eyes with a history of proliferative diabetic retinopathy (PDR) or chronic uveitis. We retrospectively studied the results of combined extracapsular cataract extraction (ECCE), posterior chamber intraocular lens (PC-IOL) implantation, and pars plana vitrectomy in 20 eyes of 16 patients. The indications for combined vitrectomy included dense, nonclearing vitreous hemorrhage attributed to PDR in 10 eyes, age-related macular degeneration in 2, and trauma in 1. The remaining 7 eyes had pars plana vitrectomy to remove inflammatory vitreous cell and debris associated with chronic uveitis. Follow up ranged from 4 to 32 months (average, 17.4 months). Visual acuity improved in 19 eyes (95%)--to 20/100 or better in 12 (60%). The improvement ranged from 1 to 13 Snellen lines (average, 4.9 lines). Postoperative visual acuity improvement averaged 7.5 Snellen lines for eyes with chronic uveitis, 7.0 lines for those with age-related macular degeneration, and 3.3 lines for those with a history of PDR. Postoperative visual acuity was less than 20/100 in 8 eyes (40%). In most cases, these latter results were attributed to macular changes associated with the underlying ocular disease. Our results confirm previous studies that have shown that combined ECCE/PC-IOL implantation and pars plana vitrectomy is a well-tolerated surgical procedure for diabetics, which can provide clear anterior and posterior segment media. In addition, our results suggest that this combined procedure can be useful in restoring vision in certain eyes with uveitis in the short-term postoperative period.
并存的白内障与玻璃体视网膜疾病的外科治疗一直存在争议,尤其是对于有增殖性糖尿病视网膜病变(PDR)或慢性葡萄膜炎病史的眼睛。我们回顾性研究了16例患者20只眼中联合囊外白内障摘除术(ECCE)、后房型人工晶状体(PC-IOL)植入术和平部玻璃体切除术的结果。联合玻璃体切除术的适应证包括:10只眼因PDR导致的浓密、不吸收的玻璃体出血,2只眼为年龄相关性黄斑变性,1只眼为外伤。其余7只眼行平部玻璃体切除术以清除与慢性葡萄膜炎相关的炎性玻璃体细胞和碎屑。随访时间为4至32个月(平均17.4个月)。19只眼(95%)视力改善,其中12只眼(60%)视力提高到20/100或更好。视力提高范围为1至13行Snellen视力表(平均4.9行)。慢性葡萄膜炎患者术后视力平均提高7.5行Snellen视力表,年龄相关性黄斑变性患者为7.0行,有PDR病史患者为3.3行。8只眼(40%)术后视力低于20/100。在大多数情况下,这些较差的结果归因于与潜在眼部疾病相关的黄斑病变。我们的结果证实了先前的研究,即ECCE/PC-IOL植入术和平部玻璃体切除术联合应用对糖尿病患者是一种耐受性良好的手术方法,可使眼前段和后段介质清晰。此外,我们的结果表明,这种联合手术在术后短期内可有助于恢复某些葡萄膜炎患者的视力。