Wilson D A
Department of Zoology, University of Oklahoma, Norman, OK 73019, USA.
Chem Senses. 2001 Jun;26(5):577-84. doi: 10.1093/chemse/26.5.577.
Current models of odor discrimination in mammals involve molecular feature detection by a large family of diverse olfactory receptors, refinement of molecular feature extraction through precise projections of olfactory receptor neurons to the olfactory bulb to form an odor-specific spatial map of molecular features across glomerular layer, and synthesis of these features into odor objects within the piriform cortex. This review describes our recent work on odor and spatial receptive fields within the anterior piriform cortex and compares these fields with receptive fields of their primary afferent, olfactory bulb mitral/tufted cells. The results suggest that receptive fields in the piriform cortex are ensemble in nature, highly dynamic, and may contribute to odor discrimination and odor memory.
目前哺乳动物气味辨别模型涉及一大类多样的嗅觉受体进行分子特征检测，通过嗅觉受体神经元向嗅球的精确投射来细化分子特征提取，从而在肾小球层形成分子特征的气味特异性空间图谱，并将这些特征合成为梨状皮质内的气味对象。本综述描述了我们最近关于前梨状皮质内气味和空间感受野的研究工作，并将这些感受野与其主要传入神经嗅球二尖瓣/簇状细胞的感受野进行了比较。结果表明，梨状皮质中的感受野本质上是集合性的，具有高度动态性，可能有助于气味辨别和气味记忆。
