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大鼠组织在微波频率下介电特性随年龄的变化。

Changes in the dielectric properties of rat tissue as a function of age at microwave frequencies.

作者信息

Peyman A, Rezazadeh A A, Gabriel C

机构信息

Department of Electronic Engineering, King's College London, UK.

出版信息

Phys Med Biol. 2001 Jun;46(6):1617-29. doi: 10.1088/0031-9155/46/6/303.

Abstract

The dielectric properties of ten rat tissues at six different ages were measured at 37 degrees C in the frequency range of 130 MHz to 10 GHz using an open-ended coaxial probe and a computer controlled network analyser. The results show a general decrease of the dielectric properties with age. The trend is more apparent for brain, skull and skin tissues and less noticeable for abdominal tissues. The variation in the dielectric properties with age is due to the changes in the water content and the organic composition of tissues. The percentage decrease in the dielectric properties of certain tissues in the 30 to 70 day old rats at cellular phone frequencies have been tabulated. These data provide an important input in the provision of rigorous dosimetry in lifetime-exposure animal experiments. The results provide some insight into possible differences in the assessment of exposure for children and adults.

摘要

使用开放式同轴探头和计算机控制的网络分析仪,在37摄氏度下,于130兆赫兹至10吉赫兹的频率范围内测量了六个不同年龄段的十只大鼠组织的介电特性。结果表明,介电特性总体上随年龄增长而降低。这种趋势在脑、颅骨和皮肤组织中更为明显,而在腹部组织中则不太明显。介电特性随年龄的变化是由于组织中水分含量和有机成分的变化。已将30至70日龄大鼠在手机频率下某些组织介电特性的百分比下降情况制成表格。这些数据为在终身暴露动物实验中提供严格的剂量测定提供了重要依据。研究结果为深入了解儿童和成人暴露评估中可能存在的差异提供了一些线索。

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