Zywietz F, Knöchel R
Phys Med Biol. 1986 Sep;31(9):1021-9. doi: 10.1088/0031-9155/31/9/007.
The dielectric properties of a rat tumour (rhabdomyosarcoma R1H), skin and muscle were measured in vivo with an open-ended coaxial line and a computer-controlled system based on a network analyser. The permittivity of the tumour R1H and of the normal tissues in anaesthetised rats was determined at frequencies between 0.2 and 2.4 GHz. No significant differences were observed either between rat tumour and muscle or between normal and 15 Gy irradiated rat tumour and skin. However, after a hyperthermia treatment at 43 degrees C for 60 min the dielectric properties, especially of the rat skin, changed due to the hyperthermic induced oedema which is related to an increase in tissue water content. The process of the oedema modifies the dielectric properties of the skin to a higher degree than those of the tumour.
采用开口同轴探头和基于网络分析仪的计算机控制系统，在体内测量了大鼠肿瘤（横纹肌肉瘤R1H）、皮肤和肌肉的介电特性。在0.2至2.4GHz频率范围内，测定了麻醉大鼠体内肿瘤R1H和正常组织的介电常数。未观察到大鼠肿瘤与肌肉之间、正常大鼠肿瘤及皮肤与15Gy照射后的大鼠肿瘤及皮肤之间存在显著差异。然而，在43℃进行60分钟的热疗后，由于热诱导水肿导致组织含水量增加，介电特性发生了变化，尤其是大鼠皮肤的介电特性。水肿过程对皮肤介电特性的改变程度高于肿瘤。
