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稀释的菊科混合物与倍半萜内酯混合物作为菊科皮炎筛查剂的多中心研究

Diluted Compositae mix versus sesquiterpene lactone mix as a screening agent for Compositae dermatitis: a multicentre study.

作者信息

Bong J L, English J S, Wilkinson S M

机构信息

Department of Dermatology, Queen's Medical Centre, Nottingham, UK.

出版信息

Contact Dermatitis. 2001 Jul;45(1):26-8. doi: 10.1034/j.1600-0536.2001.045001026.x.

DOI:10.1034/j.1600-0536.2001.045001026.x
PMID:11422264
Abstract

The objective of this study was to compare diluted Compositae mix with sesquiterpene lactone mix as a marker for Compositae dermatitis. Patients undergoing diagnostic patch testing in 8 British Isles patch test centres were also patch tested to sesquiterpene lactone mix (0.1% pet.) and Compositae mix (3% pet. or 0.6% pet.). Of a total of 5574 patients tested, 71 (1.3%) reacted to Compositae mix, 57 (1.0%) reacted to sesquiterpene lactone mix, and 45 to both. Diluted Compositae mix remained a more sensitive screening marker for Compositae allergy. We recommend that patients are patch tested to both agents.

摘要

本研究的目的是比较稀释的菊科混合物与倍半萜内酯混合物作为菊科皮炎标志物的效果。在不列颠群岛8个斑贴试验中心接受诊断性斑贴试验的患者,也接受了倍半萜内酯混合物(0.1% 凡士林制剂)和菊科混合物(3% 凡士林制剂或0.6% 凡士林制剂)的斑贴试验。在总共5574名接受检测的患者中,71名(1.3%)对菊科混合物有反应,57名(1.0%)对倍半萜内酯混合物有反应,45名对两者都有反应。稀释的菊科混合物仍是菊科过敏更敏感的筛查标志物。我们建议对患者进行这两种制剂的斑贴试验。

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