实验感染猪霍乱病毒的猪细支气管上皮中的非典型纤毛。

Atypical cilia in the bronchiolar epithelium of pigs experimentally infected with hog cholera virus.

作者信息

Carrasco L, Ruiz-Villamor E, Gómez-Villamandos J C, Bautista M J, Nuñez A, Quezada M, Sierra M A

机构信息

Departamento de Anatomía y Anatomía Patológica Comparadas, Edificio de Sanidad Animal, Facultad de Veterinaria, Universidad de Córdoba, Campus Universitario de Rabanales, 14014 Córdoba, Spain.

出版信息

J Comp Pathol. 2001 Jan;124(1):29-35. doi: 10.1053/jcpa.2000.0424.

DOI:10.1053/jcpa.2000.0424

PMID:11428186

Abstract

To study the effect of hog cholera virus on the epithelial cells of the bronchiolar mucosa, 12 pigs were inoculated with a highly virulent strain. Immunohistochemical and ultrastructural examination of the ciliated epithelial cells demonstrated an increase in the number of atypical cilia. The latter showed alterations in the microtubular pattern, possibly resulting from viral interference with the normal metabolism of the epithelial cells.

摘要

为研究猪霍乱病毒对细支气管黏膜上皮细胞的影响，给12头猪接种了高毒株。对纤毛上皮细胞进行免疫组织化学和超微结构检查发现，非典型纤毛数量增加。后者显示微管模式发生改变，这可能是病毒干扰上皮细胞正常代谢所致。