Tringali C, Spatafora C, Calì V, Simmonds M S
Dipartimento di Scienze Chimiche, Università di Catania, Viale A. Doria 6, Catania I-95125, Italy.
Fitoterapia. 2001 Jun;72(5):538-43. doi: 10.1016/s0367-326x(01)00265-9.
Analysis of the polar fractions of an EtOH extract obtained from the bark of the African medicinal plant Fagara macrophylla led to the isolation and identification of the alkaloids oblongine (6), tembetarine (7) and magnoflorine (8) and the flavonoid hesperidin (9). These compounds, together with other metabolites (1--5) previously isolated from F. macrophylla, were tested for antifeedant activity in a binary-choice bioassay. The acridone alkaloid xanthoxoline (4) was found to have a potent antifeedant activity against larvae of both Spodoptera frugiperda and S. littoralis. 1-Hydroxy-3-methoxy-N-methyl-acridone (2), arborinine (3), tembetarine (7) and magnoflorine (8) were antifeedant against S. frugiperda.
对从非洲药用植物大叶崖椒树皮中提取的乙醇提取物的极性部分进行分析，导致了生物碱长圆叶花椒碱（6）、去甲乌药碱（7）和木兰碱（8）以及类黄酮橙皮苷（9）的分离和鉴定。这些化合物，连同先前从大叶崖椒中分离出的其他代谢物（1 - 5），在二元选择生物测定中测试了拒食活性。发现吖啶酮生物碱花椒喹啉（4）对草地贪夜蛾和海滨夜蛾的幼虫都有很强的拒食活性。1 - 羟基 - 3 - 甲氧基 - N - 甲基吖啶酮（2）、树豆碱（3）、去甲乌药碱（7）和木兰碱（8）对草地贪夜蛾有拒食作用。
