子宫收缩力的生理基础：简要综述。
The physiological basis of uterine contractility: a short review.
作者信息
Wray S, Kupittayanant S, Shmygol A, Smith R D, Burdyga T
机构信息
The Physiological Laboratory, The University of Liverpool, Crown Street, Liverpool L69 3BX, UK.
出版信息
Exp Physiol. 2001 Mar;86(2):239-46. doi: 10.1113/eph8602114.
In this review we discuss our current understanding of the cellular basis of uterine contractility, highlighting those areas requiring further study. It is clear that the basic processes of excitation-contraction coupling lie within the myometrial cell, and that these may be modified by agonists. Pacemaker activity, however, remains a mystery. The contribution of extracellular calcium entry to contraction is shown to be vital, whilst the role of the sarcoplasmic reticulum remains controversial. Much current experimental focus is on pathways controlling and regulating contraction, and we discuss sensitisation mechanisms and question their role in intact uterine preparations. Experimental Physiology (2001) 86.2, 239-246.
在本综述中，我们讨论了目前对子宫收缩细胞基础的理解，重点强调了那些需要进一步研究的领域。很明显，兴奋 - 收缩偶联的基本过程发生在子宫肌层细胞内，并且这些过程可能会被激动剂改变。然而，起搏活动仍然是个谜。细胞外钙内流对收缩的作用至关重要，而肌浆网的作用仍存在争议。目前许多实验重点在于控制和调节收缩的途径，我们讨论了致敏机制并质疑它们在完整子宫制剂中的作用。《实验生理学》（2001年）86.2，239 - 246页。
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