从葡萄糖供体立体选择性合成2-羟基-α-甘露吡喃糖苷。

Stereoselective synthesis of 2-hydroxy-alpha-mannopyranosides from glucal donors.

作者信息

Kim J Y, Di Bussolo V, Gin D Y

机构信息

Department of Chemistry, University of Illinois at Urbana-Champaign, Urbana, Illinois 61801, USA.

出版信息

Org Lett. 2001 Jan 25;3(2):303-6. doi: 10.1021/ol006941y.

DOI:10.1021/ol006941y

PMID:11430060

Abstract

[figure: see text] Direct synthetic access to 2-hydroxy-alpha-mannopyranosides from glucal donors is accomplished via a one-pot stereoselective oxidative glycosylation reaction, employing the reagent combination of dibenzothiophene bis(triflate) and dibenzothiophene-5-oxide.

摘要

[图：见正文] 通过一锅法立体选择性氧化糖基化反应，使用二苯并噻吩双（三氟甲磺酸酯）和二苯并噻吩 -5-氧化物的试剂组合，可直接从葡萄糖供体合成2-羟基-α-甘露吡喃糖苷。