Johannesen Sine A, Petersen Bent O, Duus Jens O, Skrydstrup Troels
Department of Chemistry and Interdisciplinary Nanoscience Center, University of Aarhus, Langelandsgade 140, 8000 Aarhus C, Denmark.
Inorg Chem. 2007 May 14;46(10):4326-35. doi: 10.1021/ic070016r. Epub 2007 Apr 20.
X-ray and NMR experiments were performed with simple chitosan models based on glucosamine monosaccharides and disaccharides to understand the binding properties and structures of the complexes formed between this polysaccharide and platinum(II) metals. Subjection of the glucosamine derivatives with [PdCl2(PhCN)2] provided trans-diamine complexes which upon further treatment with excess (NH4)PF6 generated complexes possessing two 5-membered chelate rings involving the C2-amine and the C3-hydroxyl group of the two individual glucosamine units.
利用基于氨基葡萄糖单糖和二糖的简单壳聚糖模型进行了X射线和核磁共振实验，以了解这种多糖与铂（II）金属形成的配合物的结合特性和结构。氨基葡萄糖衍生物与[PdCl2(PhCN)2]反应生成反式二胺配合物，该配合物经进一步用过量的(NH4)PF6处理后，生成了具有两个五元螯合环的配合物，这两个螯合环涉及两个单独氨基葡萄糖单元的C2-胺基和C3-羟基。
