Türktaş I, Bostanci I, Altuntaş B
Department of Pediatric Allergy and Asthma, Gazi University Faculty of Medicine, Ankara, Turkey.
Turk J Pediatr. 2001 Apr-Jun;43(2):151-4.
Patients with ulcerative colitis may have a presentation dominated by extraintestinal manifestations. These manifestations, particularly bronchiectasis, are very rarely seen in pediatric patients. A 13-year-old boy with ulcerative colitis who was diagnosed by colonic mucosa biopsy is presented. He developed unexplained productive cough after the appearance of colonic disease. He was treated and followed up at his primary care hospital with the sole diagnosis of ulcerative colitis, with little attention given to the chest symptoms. The relation of the bronchial involvement to the ulcerative colitis was not established until two years after the onset of disease. Thoracal computed tomography (CT) examination after this period showed evidence of bronchiectasis and pulmonary involvement. Despite prophylactic inhaled corticosteroid treatment, no clinical or radiographic improvement was observed and widespread bronchial destruction developed very rapidly. More effective treatment with oral steroids was probably necessary in this patient, if the early chest symptoms were related to the ulcerative colitis.
溃疡性结肠炎患者可能以肠外表现为主。这些表现,尤其是支气管扩张,在儿科患者中非常罕见。本文介绍了一名13岁经结肠黏膜活检确诊为溃疡性结肠炎的男孩。他在结肠疾病出现后出现了原因不明的咳痰。他在基层医疗医院接受治疗和随访,仅诊断为溃疡性结肠炎,很少关注胸部症状。直到疾病发作两年后,支气管受累与溃疡性结肠炎的关系才得以确立。在此之后的胸部计算机断层扫描(CT)检查显示有支气管扩张和肺部受累的迹象。尽管进行了预防性吸入糖皮质激素治疗,但未观察到临床或影像学改善,且广泛的支气管破坏迅速发展。如果早期胸部症状与溃疡性结肠炎有关,该患者可能需要更有效的口服类固醇治疗。