Rabasa-Lhoret R, Rasamisoa M, Caubel C, Avignon A, Monnier L
Service des Maladies métaboliques, Hôpital Lapeyronie, CHU de Montpellier.
Presse Med. 2001;30(19):964-5.
Diagnosis of hyperparathyroidism during pregnancy is rare because symptoms are often moderate and similar to signs observed during normal pregnancy. The gravity of such an association is probably underscored.
The diagnosis of hyperparathyroidism was made at 9 weeks gestation in a young woman who declined surgery. She was seen again at 32 weeks gestation for in utero fetal death. Nine months later she accepted surgery and a parathyroid adenoma was removed.
Hyperparathyroidism during pregnancy is associated with significant morbidity with major maternal or fetal complications in 50% of the cases. Surgery during the second trimester of pregnancy is the treatment of choice. If hyperparathyroidism is diagnosed in young women who desire pregnancy, surgery should be performed before advising pregnancy.
孕期甲状旁腺功能亢进症的诊断较为罕见,因为其症状通常较轻,且与正常孕期出现的体征相似。这种关联的严重性可能未得到充分重视。
一名年轻女性在妊娠9周时被诊断为甲状旁腺功能亢进症,她拒绝接受手术。妊娠32周时,因宫内胎儿死亡再次就诊。九个月后,她接受了手术,切除了甲状旁腺腺瘤。
孕期甲状旁腺功能亢进症会引发严重的发病情况,50%的病例会出现主要的母体或胎儿并发症。妊娠中期手术是首选治疗方法。如果在渴望怀孕的年轻女性中诊断出甲状旁腺功能亢进症,应在建议怀孕前进行手术。