Ruiter N V, Müller T O, Stotzka R, Kaiser W A
Forschungszentrum Karlsruhe, Eggenstein, Germany.
J Digit Imaging. 2001 Jun;14(2 Suppl 1):52-5. doi: 10.1007/BF03190295.
Major problems in treating breast cancer are the early detection of tumors and accurate biopsy of small volumes of breast (mamma) tissue. This report presents an elastic registration algorithm of two x-ray mammograms and a corresponding magnetic resonance imaging (MRI) volume. To cope with the soft tissue deformation of the breast during mammography, a two-dimensional model of breast deformation behavior is used as an elastic transformation. Normalized mutual information is employed as a measure of similarity. Regions of interest in the uncompressed x-ray mammograms are projected into the MRI volume to determine their three-dimensional origin.
治疗乳腺癌的主要问题在于肿瘤的早期检测以及对少量乳腺组织进行准确活检。本报告提出了一种针对两张乳腺X光片以及相应的磁共振成像(MRI)容积数据的弹性配准算法。为应对乳腺X光摄影过程中乳房的软组织变形,采用乳房变形行为的二维模型作为弹性变换。使用归一化互信息作为相似性度量。将未压缩的乳腺X光片中的感兴趣区域投影到MRI容积数据中,以确定其三维原点。