Shoshani O, Ullmann Y, Shupak A, Ramon Y, Gilhar A, Kehat I, Peled I J
Department of Plastic and Reconstructive Surgery, Rambam Medical Center and Israel Naval Medical Institute, IDF Medical Corps, Haifa, Israel.
Dermatol Surg. 2001 Jul;27(7):645-7. doi: 10.1046/j.1524-4725.2001.00146.x.
The injection of autologous free fat obtained by suction-assisted lipectomy for the correction of soft tissue defects is a common procedure in plastic surgery. However, unpredictable partial absorption of the injected fat often necessitates repeated procedures.
To examine the role of frozen storage as a means of preserving the fat obtained by suction-assisted lipectomy for repeated procedures.
Human adipose tissue obtained by suction-assisted lipectomy was stored in a domestic refrigerator at -18 degrees C for 2 weeks. After thawing, the fat was injected into nude mice. In the control group, the fat was injected immediately after the harvesting procedure. Grafts were dissected out and compared 15 weeks postinjection.
Injected fat survived in both study and control groups. No significant differences were found between fat graft weight and volume, or in any of the histologic parameters examined.
Fat obtained by suction-assisted lipectomy may be preserved for future use by freezing.
通过吸脂术获取自体游离脂肪用于矫正软组织缺损是整形外科的常见手术。然而,注射脂肪不可预测的部分吸收常常需要重复手术。
探讨冷冻保存作为一种保存通过吸脂术获取的脂肪以供重复手术使用的方法的作用。
通过吸脂术获取的人体脂肪组织在-18℃的家用冰箱中储存2周。解冻后,将脂肪注射到裸鼠体内。在对照组中,脂肪在采集后立即注射。注射15周后取出移植物并进行比较。
研究组和对照组中注射的脂肪均存活。脂肪移植物的重量和体积,或在所检查的任何组织学参数方面均未发现显著差异。
通过吸脂术获取的脂肪可通过冷冻保存以备将来使用。