Neaigus A, Miller M, Friedman S R, Des Jarlais D C
Center for Drug Use and HIV Research, National Development and Research Institutes, Inc., New York, NY 10048, USA.
J Infect Dis. 2001 Aug 1;184(3):359-63. doi: 10.1086/322020. Epub 2001 Jun 26.
To assess whether human immunodeficiency virus (HIV)-infected and/or hepatitis C virus (HCV)-infected noninjecting heroin users (NIUs) are a potential sexual transmission bridge to "lower risk" partners, 180 HIV- or HCV-infected NIUs recruited in New York City were interviewed about their sexual behaviors and partnerships. Sixty-two percent were former injecting drug users (IDUs). Partners reported not to be HIV infected, IDUs, or men who have sex with men were defined as lower risk. Among 54 HIV-infected NIUs, lower risk partners were reported by 54% of never IDUs and 23% of former IDUs (P=.02). Among 155 HCV-infected NIUs, lower risk partners were reported by 54% of never IDUs and 45% of former IDUs (not significant). Engaging in unprotected vaginal or anal sex and having lower risk partners was reported by 29% of HIV-infected never IDUs, 12% of HIV-infected former IDUs, 29% of HCV-infected never IDUs, and 34% of HCV-infected former IDUs. HIV-infected NIUs, particularly never IDUs, and, possibly, HCV-infected NIUs, are a potential sexual transmission bridge.
为评估感染人类免疫缺陷病毒（HIV）和/或丙型肝炎病毒（HCV）的非注射海洛因使用者（NIUs）是否会成为向“低风险”伴侣进行性传播的潜在桥梁，研究人员对在纽约市招募的180名感染HIV或HCV的NIUs进行了访谈，了解他们的性行为和性伴侣情况。62%的人曾是注射吸毒者（IDUs）。报告其伴侣未感染HIV、不是IDUs或不是男男性行为者的被定义为低风险。在54名感染HIV的NIUs中，54%的从未注射吸毒者和23%的曾注射吸毒者报告有低风险伴侣（P = 0.02）。在155名感染HCV的NIUs中，54%的从未注射吸毒者和45%的曾注射吸毒者报告有低风险伴侣（无统计学意义）。29%的从未注射吸毒的HIV感染者、12%的曾注射吸毒的HIV感染者、29%的从未注射吸毒的HCV感染者和34%的曾注射吸毒的HCV感染者报告有未采取保护措施的阴道或肛交行为以及有低风险伴侣。感染HIV的NIUs，尤其是从未注射吸毒者，以及可能感染HCV的NIUs，是潜在的性传播桥梁。
