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饮酒严重程度对非法药物使用者的性风险行为和 HIV 暴露的作用。

The role of drinking severity on sex risk behavior and HIV exposure among illicit drug users.

机构信息

Department of Mental Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 21205, USA.

出版信息

Am J Addict. 2013 May-Jun;22(3):239-45. doi: 10.1111/j.1521-0391.2012.12006.x.

Abstract

OBJECTIVES

The current study examined how drinking severity among injection and non-injection drug users is associated with sex risk behaviors and risk of HIV exposure.

METHOD

The study is a secondary analysis of an investigation of risk factors among drug users in Baltimore known as the NEURO-HIV epidemiologic study. Participants (N = 557) completed an interview, self-reported 30-day alcohol use, lifetime injection and non-injection drug use, and provided blood samples to screen for HIV. Participants were grouped into one of three drinking severity conditions: abstinent (no reported alcohol use in prior 30 days), moderate alcohol use (≤30 drinks for females, or ≤60 drinks for males), or problematic alcohol use (>30 drinks for females, or >60 drinks for males). Drinking severity groups were significantly different on lifetime injection drug use, heroin injection, snorting/sniffing cocaine, and smoking crack.

RESULTS

Logistic regression analyses found problematic alcohol users to be more likely than alcohol abstainers to inject drugs before or during sex (AOR = 5.78; 95% CI = 2.07-16.10), and more likely than moderate alcohol users to use alcohol before/during sex (AOR = 4.96; 95% CI = 2.09-11.81), inject drugs before/during sex (AOR = 2.96; 95% CI = 1.29-6.80), and to be HIV+ among Black participants (AOR = 2.72; 95% CI = 1.14-6.49).

CONCLUSIONS

These results outline the necessity for research and clinical intervention among this population to reduce sex risk behaviors and potential HIV exposure, while highlighting the need to examine drinking severity as a predictor of sex risk behaviors.

摘要

目的

本研究旨在探讨注射和非注射吸毒者的饮酒严重程度与性行为风险行为和 HIV 暴露风险之间的关系。

方法

本研究是对巴尔的摩吸毒者危险因素调查(即 NEURO-HIV 流行病学研究)的二次分析。参与者(N=557)完成了访谈,自我报告了 30 天的酒精使用情况、终生注射和非注射药物使用情况,并提供了血液样本以筛查 HIV。参与者被分为以下三种饮酒严重程度组别之一:禁欲(过去 30 天内无报告饮酒)、适度饮酒(女性≤30 杯,男性≤60 杯)或有问题的饮酒(女性>30 杯,男性>60 杯)。饮酒严重程度组在终生注射药物使用、海洛因注射、吸食可卡因和吸食快克可卡因方面存在显著差异。

结果

逻辑回归分析发现,有问题的饮酒者比禁欲者更有可能在性行为之前或期间注射毒品(AOR=5.78;95%CI=2.07-16.10),并且比适度饮酒者更有可能在性行为之前/期间饮酒(AOR=4.96;95%CI=2.09-11.81)、在性行为之前/期间注射毒品(AOR=2.96;95%CI=1.29-6.80),以及在黑人参与者中 HIV 阳性(AOR=2.72;95%CI=1.14-6.49)。

结论

这些结果概述了在该人群中进行研究和临床干预的必要性,以减少性行为风险行为和潜在的 HIV 暴露,同时强调需要将饮酒严重程度作为性行为风险行为的预测指标进行研究。

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