Diaz-Buxo J A
Peritoneal Dialysis Services, Fresenius Medical Care North America, Charlotte, North Carolina, USA.
J Am Soc Nephrol. 1998 Dec;9(12 Suppl):S112-7.
Dialysis modality selection should be based on patient preference and medical indications. Every effort should be made to provide adequate dosing of dialysis by using guidelines supported by clinical outcome evidence. All patients should receive explicit information on all modalities of therapy, including transplantation, in a balanced presentation before initiation of dialysis. The patient should be an active participant in the selection process. The advantages, disadvantages, indications, and contraindications for hemodialysis and the various modalities of peritoneal dialysis are reviewed in light of the state of the art knowledge. Further research is critical to answer three unresolved issues: (1) What are the equivalent doses for peritoneal dialysis and hemodialysis? (2) Are dialytic and renal clearances equivalent? and (3) Will survival improve by providing peritoneal dialysis doses above those currently recommended?
透析方式的选择应基于患者的偏好和医学指征。应尽一切努力通过采用有临床结局证据支持的指南来提供足够的透析剂量。在开始透析前,应以平衡的方式向所有患者提供包括移植在内的所有治疗方式的明确信息。患者应积极参与选择过程。根据最新的知识水平,对血液透析和各种腹膜透析方式的优缺点、适应证和禁忌证进行了综述。进一步的研究对于回答三个未解决的问题至关重要:(1)腹膜透析和血液透析的等效剂量是多少?(2)透析清除率和肾脏清除率是否等效?以及(3)提供高于目前推荐剂量的腹膜透析是否会提高生存率?