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芬兰与职业因素相关死亡比例的流行病学估计。

Epidemiologic estimate of the proportion of fatalities related to occupational factors in Finland.

作者信息

Nurminen M, Karjalainen A

机构信息

Department of Epidemiology and Biostatistics, Finnish Institute of Occupational Health, Helsinki.

出版信息

Scand J Work Environ Health. 2001 Jun;27(3):161-213. doi: 10.5271/sjweh.605.

Abstract

OBJECTIVES

This study attempts to estimate the proportion of annual deaths related to occupational factors in Finland and considers related methodological issues and associated uncertainties.

METHODS

Statistics on causes of death, numbers of subjects exposed, and risk ratios obtained from the epidemiologic literature were used to estimate the population attributable fraction and disease burden for causes of death from work-related diseases. Gender-, age- and disease-specific numbers of deaths were provided by Statistics Finland for 1996. Information on the size of the population, broken down by gender, age, occupation, and industry, was acquired from population censuses. A Finnish job-exposure matrix supplied data on the prevalence of exposure for specific agents and the level of exposure among exposed workers.

RESULTS

The attributable fraction of work-related mortality in the relevant disease and age categories was estimated to be 7% (10% for men and 2% for women), and for all diseases and ages the fraction was 4%. For the main cause-of-death categories, the attributable fraction became 12% for circulatory system diseases, 8% for malignant neoplasms, 4% for respiratory system diseases, 4% for mental disorders, 3% for nervous system diseases, and 3% for accidents and violence. The following estimates were obtained for specific important diseases: 24% for lung cancer, 17% for ischemic heart disease, 12% for chronic obstructive pulmonary disease, and 11% for stroke. Based on these fractions, the total number of work-related deaths that occurred in Finland in 1996 was calculated to be on the order of 1800 (employed work force of 2.1 million); 86% involved men.

CONCLUSIONS

High-quality epidemiologic studies and national survey data are essential for obtaining reliable estimates of the proportion of deaths attributable to occupational factors. The magnitude of work-related mortality is an insufficiently recognized contributor to total mortality in Finland, especially from circulatory diseases and other diseases caused by exposure to agents other than asbestos.

摘要

目的

本研究旨在估算芬兰与职业因素相关的年度死亡比例,并探讨相关方法问题及不确定性。

方法

利用从流行病学文献中获取的死亡原因统计数据、暴露人群数量及风险比,来估算与工作相关疾病导致的死亡原因的人群归因分数及疾病负担。芬兰统计局提供了1996年按性别、年龄和疾病分类的死亡人数。按性别、年龄、职业和行业划分的人口规模信息则取自人口普查。一份芬兰工作暴露矩阵提供了特定暴露源的暴露流行率及暴露工人的暴露水平数据。

结果

相关疾病和年龄类别中与工作相关死亡率的归因分数估计为7%(男性为10%,女性为2%),所有疾病和年龄的归因分数为4%。对于主要死因类别,循环系统疾病的归因分数为12%,恶性肿瘤为8%,呼吸系统疾病为4%,精神障碍为4%,神经系统疾病为3%,事故和暴力为3%。对于特定重要疾病,得出以下估计值:肺癌为24%,缺血性心脏病为17%,慢性阻塞性肺疾病为12%,中风为11%。根据这些分数,计算出1996年芬兰发生的与工作相关死亡总数约为1800例(就业劳动力为210万);其中86%涉及男性。

结论

高质量的流行病学研究和国家调查数据对于可靠估算职业因素导致的死亡比例至关重要。在芬兰,与工作相关的死亡率对总死亡率的贡献未得到充分认识,尤其是对于循环系统疾病和由石棉以外的暴露因素引起的其他疾病。

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