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爱德华·阿尔伯特·谢弗(夏普伊-谢弗)及其对神经科学的贡献:纪念其诞辰150周年。

Edward Albert Schäfer (Sharpey-Schafer) and his contributions to neuroscience: commemorating of the 150th anniversary of his birth.

作者信息

Sparrow E P, Finger S

机构信息

Department of Psychology, Washington University, St. Louis, MO 63130-4899, USA.

出版信息

J Hist Neurosci. 2001 Mar;10(1):41-57. doi: 10.1076/jhin.10.1.41.5625.

DOI:10.1076/jhin.10.1.41.5625
PMID:11446263
Abstract

The year 2000 marks the 150th anniversary of the birth of Edward Albert Schäfer (Sir Edward Albert Sharpey-Schafer). Affiliated first with University College, London, and then with Edinburgh University, Schäfer made monumental contributions to the fields of histology, physiology, endocrinology, and practical medicine. This paper traces his professional life and emphasizes his seminal contributions to the neurosciences, which include his findings in support of neuron doctrine, his research on cortical localization in monkeys, his discovery of adrenaline and its place in the history of neural transmission, and his studies on recovery after nerve damage. Author of many histology and physiology books, founder of the "Quarterly Journal of Experimental Physiology," and mentor to many students who achieved great fame themselves, Schäfer was an active teacher and researcher, a man who remained committed to his vision of medicine based on laboratory science until he died in 1935.

摘要

2000年是爱德华·阿尔伯特·谢弗(爱德华·阿尔伯特·沙尔皮-谢弗爵士)诞辰150周年。谢弗最初隶属于伦敦大学学院,后来又与爱丁堡大学有关联,他在组织学、生理学、内分泌学和临床医学领域做出了巨大贡献。本文追溯了他的职业生涯,并着重介绍了他对神经科学的开创性贡献,其中包括他支持神经元学说的发现、对猴子大脑皮层定位的研究、肾上腺素的发现及其在神经传递史上的地位,以及他对神经损伤后恢复情况的研究。谢弗著有多本组织学和生理学书籍,是《实验生理学季刊》的创始人,也是许多后来声名远扬的学生的导师。他是一位活跃的教师和研究者,直到1935年去世,他始终坚持基于实验室科学的医学理念。

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