Rodolakis A, Papaspyrou I, Sotiropoulou M, Markaki S, Michalas S
1st Department of Obstetrics and Gynecology, Athens University, Greece.
Eur J Gynaecol Oncol. 2001;22(2):143-6.
Primary squamous cell carcinoma of the endometrium (PSCCE) is a rare disease of unknown etiology. Diagnosis is based on the identification of squamous cell carcinoma in the endometrium with no coexisting analogous cervical component or endometrial adenocarcinoma. There must also be no connection between the endometrial tumour and the squamous epithelium of the cervix. Although the majority of patients are classified as stage I disease, prognosis is rather dismal. We report two new cases of primary squamous cell carcinoma of the endometrium which fulfill all the above criteria and we discuss another interesting case of squamous cell carcinoma of questionable endometrial origin. Management by abdominal hysterectomy and adjuvant pelvic irradiation resulted in long-term survival of our patients.
子宫内膜原发性鳞状细胞癌（PSCCE）是一种病因不明的罕见疾病。诊断基于在子宫内膜中识别出鳞状细胞癌，且不存在并存的类似宫颈成分或子宫内膜腺癌。子宫内膜肿瘤与宫颈鳞状上皮之间也必须没有联系。尽管大多数患者被归类为I期疾病，但其预后相当不佳。我们报告了两例符合上述所有标准的子宫内膜原发性鳞状细胞癌新病例，并讨论了另一例子宫内膜起源存疑的鳞状细胞癌有趣病例。通过腹式子宫切除术和辅助盆腔放疗进行治疗，使我们的患者获得了长期生存。
