Houissa-Vuong S, Catanzano-Laroudie M, Baviera E, Balaton A, Galet B, Gedeon I, Vuong P N
Centre de Pathologie, Bièvres, France.
Diagn Cytopathol. 2002 Nov;27(5):291-3. doi: 10.1002/dc.10186.
Primary squamous cell carcinoma of the endometrium (PSCCE) is an exceedingly rare tumor. Rarely are cytological criteria discussed. We report our experience in the cytological diagnosis of a case. A postmenopausal, 64-yr-old woman suffered from pyometria. An endometrial Pap smear displayed some malignant squamous cells. Curettage of the cervix and the uterine cavity only recovered some fragments of atypical squamous epithelium whose origin could not be precisely identified. A hysterectomy with bilateral adnexectomy was decided upon. Pathological study evidenced a primary squamous cell carcinoma in the uterine cavity while the cervix was tumor-free and the lymph nodes were devoid of metastases (pT1, pN0, pM0). The patient died 46 mo PO with multiple pulmonary and renal metastases. The histological feature of PSCCE is identical to that of any tumor of a similar nature, whatever the site, especially the cervix. Confirmation of the primary endometrial nature is only possible on the hysterectomy specimen.
子宫内膜原发性鳞状细胞癌（PSCCE）是一种极为罕见的肿瘤。很少有关于细胞学标准的讨论。我们报告了一例细胞学诊断的经验。一名64岁的绝经后女性患有子宫积脓。子宫内膜巴氏涂片显示有一些恶性鳞状细胞。宫颈和子宫腔刮除术仅获取了一些无法精确确定来源的非典型鳞状上皮碎片。遂决定行子宫切除术及双侧附件切除术。病理研究证实子宫腔内为原发性鳞状细胞癌，而宫颈无肿瘤，淋巴结无转移（pT1，pN0，pM0）。该患者术后46个月死于多发肺转移和肾转移。PSCCE的组织学特征与任何性质类似的肿瘤相同，无论其部位如何，尤其是宫颈。只有在子宫切除标本上才能确认原发性子宫内膜的性质。
