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择期瓣膜置换术中常规围手术期经食管超声心动图的前瞻性研究:临床影响及成本节约意义

Prospective study of routine perioperative transesophageal echocardiography for elective valve replacement: clinical impact and cost-saving implications.

作者信息

Ionescu A A, West R R, Proudman C, Butchart E G, Fraser A G

机构信息

Department of Cardiology, University of Wales College of Medicine, Cardiff, UK.

出版信息

J Am Soc Echocardiogr. 2001 Jul;14(7):659-67. doi: 10.1067/mje.2001.112101.

Abstract

Transesophageal echocardiography (TEE) is widely used during heart valve replacement operations, but its clinical impact and cost-saving profile have not been studied prospectively for this indication. We investigated the clinical benefits and cost-savings of routine TEE for elective valve replacement at a regional tertiary center. We prospectively studied 300 patients (140 men; mean age [+/-SD], 66 +/- 9 years) undergoing aortic valve, mitral valve, or double-valve replacements. Transesophageal echocardiography with a biplane (in 161 patients) or a multiplane probe was performed before and after surgery. We assessed whether the TEE findings changed the operation or the postoperative treatment and the cost of TEE either as an extension of a preexisting service or as a new development. In 2 patients undergoing aortic valve replacement, significant mitral regurgitation on TEE led to additional mitral valve replacement, and in 1 patient undergoing mitral valve replacement, aortic regurgitation also required aortic valve replacement. Immediate reoperation (dehisced mitral valve prosthesis) and delayed extubation (suspected obstruction of an aortic valve prosthesis) were prompted by postoperative TEE. Extending an existing TEE service to routine intraoperative use saved up to $109 (US) per patient per year. Routine intraoperative TEE can provide major clinical benefit to a small proportion of patients undergoing elective valve replacement, and this can lead to cost savings, but only if the service can be provided without major capital investment.

摘要

经食管超声心动图(TEE)在心脏瓣膜置换手术中被广泛应用,但其在此适应证方面的临床影响和成本效益尚未进行前瞻性研究。我们在一家地区三级中心调查了常规TEE用于择期瓣膜置换的临床益处和成本节约情况。我们前瞻性研究了300例接受主动脉瓣、二尖瓣或双瓣膜置换的患者(140例男性;平均年龄[±标准差],66±9岁)。在手术前后使用双平面(161例患者)或多平面探头进行经食管超声心动图检查。我们评估了TEE检查结果是否改变了手术或术后治疗,以及将TEE作为现有服务的扩展或新开展项目的成本。在2例接受主动脉瓣置换的患者中,TEE显示的严重二尖瓣反流导致了额外的二尖瓣置换;在1例接受二尖瓣置换的患者中,主动脉反流也需要进行主动脉瓣置换。术后TEE促使了即刻再次手术(二尖瓣人工瓣膜裂开)和延迟拔管(怀疑主动脉瓣人工瓣膜梗阻)。将现有的TEE服务扩展至常规术中使用,每位患者每年可节省高达109美元(美国)。常规术中TEE可为一小部分接受择期瓣膜置换的患者带来重大临床益处,且可实现成本节约,但前提是该服务无需大量资本投入即可提供。

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