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弥漫性特发性骨肥厚(DISH)中的脊髓和马尾神经受压

Spinal cord and cauda equina compression in 'DISH'.

作者信息

Sharma R R, Mahapatra A, Pawar S J, Sousa J, Lad S D, Athale S D

机构信息

Department of Neurosurgery, The National Neurosurgical Centre, Khoula Hospital, Mina-Al-Fahal, Muscat, Sultanate of Oman.

出版信息

Neurol India. 2001 Jun;49(2):148-52.

Abstract

Diffuse idiopathic skeletal hyperostosis (DISH) has long been regarded as a benign asymptomatic clinical entity with an innocuous clinical course. Precise information is lacking in the world literature. Authors report the results of a retrospective analysis of 74 cases of DISH. Eleven patients presented with progressive spinal cord or cauda equina compression. In nine cases ossified posterior longitudinal ligament (OPLL) and in two cases ossified ligamentum flavum (OLF) were primarily responsible. Surgically treated patients (eight) had far better outcome as compared to the patients managed conservatively, as they had refused surgery. 'DISH' is neither a benign condition, nor it always runs a innocuous clinical course. In fact, in about 15% of the cases, serious neurological manifestations occur, which may require a major neurosurgical intervention.

摘要

弥漫性特发性骨肥厚(DISH)长期以来一直被视为一种良性、无症状的临床病症,临床病程无害。世界文献中缺乏确切信息。作者报告了对74例DISH病例的回顾性分析结果。11例患者出现进行性脊髓或马尾神经受压。其中9例主要由后纵韧带骨化(OPLL)引起,2例由黄韧带骨化(OLF)引起。接受手术治疗的患者(8例)与拒绝手术而接受保守治疗的患者相比,预后要好得多。“DISH”既不是一种良性病症,其临床病程也并非总是无害。事实上,约15%的病例会出现严重的神经学表现,可能需要进行大型神经外科手术干预。

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