Mizuno J, Nakagawa H, Isobe M
Department of Neurological Surgery, Aichi Medical University, Japan.
No Shinkei Geka. 1998 Jan;26(1):67-72.
Two cases of ossification of the anterior longitudinal ligament (OALL) associated with diffuse idiopathic skeletal hyperostosis (DISH) presenting as dysphagia are reported. DISH has long been regarded as a radiological entity manifesting flowing ossification adjacent to the anterior and lateral borders of at least four contiguous vertebral bodies, maintenance of disc spaces, and a dearth of bony ankylosis and erosion of the apophyseal and sacroiliac joints. In the majority of cases, this entity shows an innocuous clinical course, but the dysphagia shown in our cases has also been documented in previous literature. Case 1 was a 63-year-old male developing progressive dysphagia and rhinolalia. Cervical X-rays and CT showed flowing OALL in the entire cervical spine. MRI demonstrated displacement of the trachea and esophagus by this mass. There was OALL in the thoracic and lumbar spine. Case 2 was a 62-year-old male who had undergone removal of ossification of the posterior longitudinal ligament (OPLL) from C2 to C5. He developed dysphagia and myelopathy. Cervical X-rays and CT demonstrated projection of OALL as well as posterior osteophytes at C5/6. MRI suggested that OALL had caused dysphagia, and osteophytes deteriorated myelopathy. Removal of OALL was carried out in these two cases. In case 2, removal of the osteophytes and herniated disc was carried out at the same time. Postoperative course was unremarkable with improvement of symptoms. Treatment of dysphagia due to OALL is considered to be conservative. However, surgical decompression should be considered in cases of marked projection of OALL obstructing the esophagus as shown in our cases.
报告了2例与弥漫性特发性骨肥厚(DISH)相关的前纵韧带骨化(OALL)病例,表现为吞咽困难。长期以来,DISH一直被视为一种影像学表现,其特征为至少四个连续椎体的前缘和侧缘出现连续的骨化、椎间盘间隙保持正常、无明显的骨融合以及椎小关节和骶髂关节无侵蚀。在大多数情况下,这种情况临床过程较为良性,但我们病例中出现的吞咽困难在以往文献中也有记载。病例1为一名63岁男性,出现进行性吞咽困难和鼻音。颈椎X线和CT显示整个颈椎存在连续性OALL。MRI显示该肿物使气管和食管移位。胸椎和腰椎也存在OALL。病例2为一名62岁男性,曾接受过C2至C5后纵韧带骨化(OPLL)切除术。他出现了吞咽困难和脊髓病。颈椎X线和CT显示C5/6处有OALL突出以及后骨赘。MRI提示OALL导致了吞咽困难,骨赘使脊髓病加重。对这2例患者均进行了OALL切除术。在病例2中,同时切除了骨赘和突出的椎间盘。术后病程平稳,症状改善。因OALL导致的吞咽困难通常考虑保守治疗。然而,如我们的病例所示,对于OALL明显突出并阻塞食管的情况,应考虑手术减压。