Weissman B N, Holman B L, Rosenbaum A E
Radiology. 1975 May;115(2):399-402. doi: 10.1148/115.2.399.
Radionuclide and contrast angiographies were performed in 10 dogs. In 6 dogs unilateral or bilateral (partial or total) carotid occlusions were produced by silk ligatures. Follow-up angiographies were carried out at intervals up to 6 months following surgery. Visual assessment of the radionuclide carotid angiogram was compared to quantitative analysis of the time-activity curves over these areas. Several parameters of these curves were reviewed. The ratio of the slopes, was the most sensitive parameter of the assessment of carotid artery stenosis. The ratio of the slopes of the curves in normal dogs (mean 96 plus or minus 5.2 S.D.) was significantly different from that in animals with stenosis greater than 80% (mean 67.3 plus or minus 16.9 S.D.).
对10只狗进行了放射性核素血管造影和造影血管造影。在6只狗中，用丝线结扎造成单侧或双侧（部分或完全）颈动脉闭塞。术后每隔一段时间进行随访血管造影，最长随访6个月。将放射性核素颈动脉血管造影的视觉评估与这些区域时间-活性曲线的定量分析进行比较。对这些曲线的几个参数进行了评估。斜率比是评估颈动脉狭窄最敏感的参数。正常狗曲线的斜率比（平均96±5.2标准差）与狭窄大于80%的动物曲线的斜率比（平均67.3±16.9标准差）有显著差异。
