Crook M A, Hally V, Panteli J V
Department of Chemical Pathology, Guy's and St Thomas' Hospital and University Hospital, Lewisham, London, UK.
Nutrition. 2001 Jul-Aug;17(7-8):632-7. doi: 10.1016/s0899-9007(01)00542-1.
In this review we discuss the refeeding syndrome. This potentially lethal condition can be defined as severe electrolyte and fluid shifts associated with metabolic abnormalities in malnourished patients undergoing refeeding, whether orally, enterally, or parenterally. It can be associated with significant morbidity and mortality. Clinical features are fluid-balance abnormalities, abnormal glucose metabolism, hypophosphatemia, hypomagnesemia, and hypokalemia. In addition, thiamine deficiency can occur. We describe which patient groups are more at risk for this syndrome and the clinical management of the condition.
在本综述中，我们讨论再喂养综合征。这种潜在致命的病症可定义为在接受经口、肠内或肠外再喂养的营养不良患者中，与代谢异常相关的严重电解质和液体转移。它可伴有显著的发病率和死亡率。临床特征为液体平衡异常、葡萄糖代谢异常、低磷血症、低镁血症和低钾血症。此外，还可能发生硫胺素缺乏。我们描述了哪些患者群体更易患此综合征以及该病症的临床管理。
