核孔复合体：意想不到之处的动态变化
Nuclear pore complexes: dynamics in unexpected places.
作者信息
Lyman S K, Gerace L
机构信息
Departments of Cell and Molecular Biology, The Scripps Research Institute, 10550 N. Torrey Pines Rd., La Jolla, CA 92037, USA.
出版信息
J Cell Biol. 2001 Jul 9;154(1):17-20. doi: 10.1083/jcb.200106071.
Abstract
In vivo studies on the dynamics of the nuclear pore complex (NPC) in yeast suggested that NPCs are highly mobile in the nuclear envelope. However, new evidence indicates that in mammalian cells NPCs are stably attached to a flexible lamina framework, but a peripheral component can exchange rapidly with an intranuclear pool.
摘要
对酵母细胞核孔复合体（NPC）动力学的体内研究表明，NPC在核膜中具有高度流动性。然而，新证据表明，在哺乳动物细胞中，NPC稳定地附着于一个柔性的核纤层框架，但一个外周成分可与核内池快速交换。
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