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一名神经性厌食症患者出现类似范科尼综合征的可逆性肾小管功能障碍。

Reversible tubular dysfunction that mimicked Fanconi's syndrome in a patient with anorexia nervosa.

作者信息

Alexandridis G, Liamis G, Elisaf M

机构信息

Department of Internal Medicine, Medical School, University of Ioannina, Ioannina, Greece.

出版信息

Int J Eat Disord. 2001 Sep;30(2):227-30. doi: 10.1002/eat.1078.

DOI:10.1002/eat.1078
PMID:11449459
Abstract

Patients with anorexia nervosa exhibit acid-base and electrolyte disturbances. Hypophosphatemia is commonly found in these patients during nutritional recovery. However, marked, possibly, life-threatening hypophosphatemia associated with proximal tubular dysfunction has not been previously described. We report a case of anorexia nervosa complicated by a nonacidotic proximal tubulopathy, which was manifested by renal glycosuria, as well as inappropriate phosphaturia and uricosuria resulting in hypophosphatemia and hypouricemia.

摘要

神经性厌食症患者会出现酸碱和电解质紊乱。在营养恢复过程中,这些患者常出现低磷血症。然而,之前尚未有与近端肾小管功能障碍相关的明显的、可能危及生命的低磷血症的报道。我们报告一例神经性厌食症并发非酸中毒性近端肾小管病的病例,其表现为肾性糖尿,以及不适当的磷酸盐尿和尿酸尿,导致低磷血症和低尿酸血症。

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