通过马铃薯圆盘生物测定法评估孟加拉国一些药用植物的抗肿瘤活性。

Evaluation of antitumor activity of some medicinal plants of Bangladesh by potato disk bioassay.

作者信息

Haque N, Chowdhury S A, Nutan M T, Rahman G M, Rahman K M, Rashid M A

机构信息

Department of Pharmacology, Bangabandhu Seikh Mujib Medical University, Dhaka-1000, Bangladesh.

出版信息

Fitoterapia. 2000 Sep;71(5):547-52. doi: 10.1016/s0367-326x(00)00162-3.

DOI:10.1016/s0367-326x(00)00162-3

PMID:11449504

Abstract

The antitumor activity of the ethanolic extracts of 12 medicinal plants of Bangladesh, including the vincristine-vinblastine producing Catharanthus roseus was studied using the potato disk bioassay technique. Among these, 10 plant extracts at 25.0-microgram/disc exhibited significant inhibition of crown gall tumors caused by Agrobacterium tumefaciens.

摘要

采用马铃薯圆盘生物测定技术，对包括能产生长春新碱和长春碱的长春花在内的12种孟加拉药用植物的乙醇提取物的抗肿瘤活性进行了研究。其中，10种植物提取物在25.0微克/圆盘的剂量下，对根癌土壤杆菌引起的冠瘿瘤有显著抑制作用。